Pseudomonas aeruginosa PAO1, PA3874 (narH)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse PseudoCyc / Metabolic Pathways

Gene Feature Overview

Strain Pseudomonas aeruginosa PAO1 (Stover et al., 2000)
GCF_000006765.1|latest
Locus Tag
PA3874
Name
narH
Replicon chromosome
Genomic location 4336708 - 4338249 (- strand)
Transposon Mutants 3 transposon mutants in PAO1
Transposon Mutants in orthologs 2 transposon mutants in orthologs

Cross-References

RefSeq NP_252563.1
GI 15599069
Affymetrix PA3874_narH_at
Entrez 879783
GenBank AAG07261.1
INSDC AAG07261.1
NCBI Locus Tag PA3874
protein_id(GenBank) gb|AAG07261.1|AE004804_9|gnl|PseudoCAP|PA3874
TIGR NTL03PA03874
UniParc UPI00000D4287
UniProtKB Acc G3XD87
UniProtKB ID G3XD87_PSEAE
UniRef100 UniRef100_G3XD87
UniRef50 UniRef50_P11349
UniRef90 UniRef90_A0A024HCW0

Product

Feature Type CDS
Coding Frame 1
Product Name
respiratory nitrate reductase beta chain
Product Name Confidence: Class 2
Synonyms
Evidence for Translation
Detected using LC-MS/MS (58.10 kDa, PMID:21751344)
Charge (pH 7) -6.12
Kyte-Doolittle Hydrophobicity Value -0.366
Molecular Weight (kDa) 58.1
Isoelectric Point (pI) 6.05

Subcellular localization

Individual Mappings
Localization Confidence PMID
Outer Membrane Vesicle Class 1
Cytoplasmic Membrane Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 396 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG001797 (375 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA3874
Search term: narH

Human Homologs

References

Roles of the narJ and narI gene products in the expression of nitrate reductase in Escherichia coli.
Sodergren EJ, Hsu PY, DeMoss JA
J Biol Chem 1988 Nov 5;263(31):16156-62
PubMed ID: 3053688
Proteomic analysis of outer membrane vesicles derived from Pseudomonas aeruginosa.
Choi DS, Kim DK, Choi SJ, Lee J, Choi JP, Rho S, Park SH, Kim YK, Hwang D, Gho YS
Proteomics 2011 Aug;11(16):3424-9
PubMed ID: 21751344