Strain |
Pseudomonas aeruginosa PAO1 (Stover et al., 2000)
GCF_000006765.1|latest |
Locus Tag |
PA4191
|
Name |
|
Replicon | chromosome |
Genomic location | 4688889 - 4689893 (- strand) |
Transposon Mutants | 2 transposon mutants in PAO1 |
RefSeq | NP_252880.1 |
GI | 15599386 |
Affymetrix | PA4191_at |
DNASU | PaCD00007821 |
Entrez | 880273 |
GenBank | AAG07578.1 |
INSDC | AAG07578.1 |
NCBI Locus Tag | PA4191 |
protein_id(GenBank) | gb|AAG07578.1|AE004835_7|gnl|PseudoCAP|PA4191 |
TIGR | NTL03PA04191 |
UniParc | UPI00000C5C64 |
UniProtKB Acc | Q9HWJ0 |
UniProtKB ID | Q9HWJ0_PSEAE |
UniRef100 | UniRef100_W0YWT2 |
UniRef50 | UniRef50_Q3M330 |
UniRef90 | UniRef90_W0YWT2 |
Feature Type | CDS |
Coding Frame | 1 |
Product Name |
isopenicillin-N synthase
|
Synonyms | |
Evidence for Translation | |
Charge (pH 7) | -6.65 |
Kyte-Doolittle Hydrophobicity Value | -0.310 |
Molecular Weight (kDa) | 37.4 |
Isoelectric Point (pI) | 5.81 |
Individual Mappings | |
Additional evidence for subcellular localization |
Accession | Header | Accession Date | Compound | Source | Resolution | Method | Percent Identity |
6JYV | METAL BINDING PROTEIN | 04/28/19 | Structure of an isopenicillin N synthase from Pseudomonas aeruginosa PAO1 | Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1) | 1.651 | X-RAY DIFFRACTION | 100.0 |
Results |
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 170 genera
|
Pseudomonas Ortholog Database | View orthologs at Pseudomonas Ortholog Database |
Pseudomonas Ortholog Group |
POG005153 (254 members) |
Putative Inparalogs | None Found |
STRING database | Search for predicted protein-protein interactions using:
Search term: PA4191
Search term: isopenicillin-N synthase
|
Crystal structure of isopenicillin N synthase is the first from a new structural family of enzymes.
Roach PL, Clifton IJ, Fülöp V, Harlos K, Barton GJ, Hajdu J, Andersson I, Schofield CJ, Baldwin JE
Nature 1995 Jun 22;375(6533):700-4
PubMed ID: 7791906
|
Structural characterization of an isopenicillin N synthase family oxygenase from Pseudomonas aeruginosa PAO1.
Zhang H, Che S, Wang R, Liu R, Zhang Q, Bartlam M
Biochem Biophys Res Commun 2019 Jul 5;514(4):1031-1036
PubMed ID: 31097228
|