Strain |
Pseudomonas aeruginosa PAO1 (Stover et al., 2000)
GCF_000006765.1|latest |
Locus Tag |
PA4201
|
Name |
ddlA
|
Replicon | chromosome |
Genomic location | 4700906 - 4701946 (- strand) |
Transposon Mutants | 6 transposon mutants in PAO1 |
Transposon Mutants in orthologs | 1 transposon mutants in orthologs |
RefSeq | NP_252890.1 |
GI | 15599396 |
Affymetrix | PA4201_ddlA_at |
DNASU | PaCD00007825 |
Entrez | 879033 |
GenBank | AAG07588.1 |
INSDC | AAG07588.1 |
NCBI Locus Tag | PA4201 |
protein_id(GenBank) | gb|AAG07588.1|AE004836_7|gnl|PseudoCAP|PA4201 |
TIGR | NTL03PA04201 |
UniParc | UPI00000C5C6E |
UniProtKB Acc | Q9HWI0 |
UniProtKB ID | DDLA_PSEAE |
UniRef100 | UniRef100_Q9HWI0 |
UniRef50 | UniRef50_Q9HWI0 |
UniRef90 | UniRef90_Q9HWI0 |
Feature Type | CDS |
Coding Frame | 1 |
Product Name |
D-alanine-D-alanine ligase A
|
Synonyms | |
Evidence for Translation |
Identified using nanoflow high-pressure liquid chromatography (HPLC) in conjunction with microelectrospray ionization on LTQ XL mass spectrometer (PMID:24291602).
|
Charge (pH 7) | -9.66 |
Kyte-Doolittle Hydrophobicity Value | 0.054 |
Molecular Weight (kDa) | 36.5 |
Isoelectric Point (pI) | 4.92 |
Individual Mappings | |
Additional evidence for subcellular localization |
Results |
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 596 genera
|
Pseudomonas Ortholog Database | View orthologs at Pseudomonas Ortholog Database |
Pseudomonas Ortholog Group |
POG001506 (317 members) |
Putative Inparalogs | None Found |
STRING database | Search for predicted protein-protein interactions using:
Search term: PA4201
Search term: ddlA
Search term: D-alanine-D-alanine ligase A
|
Existence of two D-alanine:D-alanine ligases in Escherichia coli: cloning and sequencing of the ddlA gene and purification and characterization of the DdlA and DdlB enzymes.
Zawadzke LE, Bugg TD, Walsh CT
Biochemistry 1991 Feb 12;30(6):1673-82
PubMed ID: 1993184
|
D-alanine: D-alanine ligase of Escherichia coli. Expression, purification and inhibitory studies on the cloned enzyme.
al-Bar OA, O'Connor CD, Giles IG, Akhtar M
Biochem J 1992 Mar 15;282 ( Pt 3)(Pt 3):747-52
PubMed ID: 1554356
|
D-alanine:D-alanine ligase: phosphonate and phosphinate intermediates with wild type and the Y216F mutant.
Fan C, Park IS, Walsh CT, Knox JR
Biochemistry 1997 Mar 4;36(9):2531-8
PubMed ID: 9054558
|