Pseudomonas aeruginosa PAO1, PA4279

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse PseudoCyc / Metabolic Pathways

Gene Feature Overview

Strain Pseudomonas aeruginosa PAO1 (Stover et al., 2000)
GCF_000006765.1|latest
Locus Tag
PA4279
Name
Replicon chromosome
Genomic location 4786734 - 4787480 (- strand)

Cross-References

RefSeq NP_252969.1
GI 15599475
Affymetrix PA4279_at
DNASU PaCD00007859
Entrez 881667
GenBank AAG07667.1
INSDC AAG07667.1
NCBI Locus Tag PA4279
protein_id(GenBank) gb|AAG07667.1|AE004843_9|gnl|PseudoCAP|PA4279
TIGR NTL03PA04280
UniParc UPI00000496CA
UniProtKB Acc Q9HWC1
UniProtKB ID COAX_PSEAE
UniRef100 UniRef100_B7V628
UniRef50 UniRef50_Q889Y6
UniRef90 UniRef90_B7V628

Product

Feature Type CDS
Coding Frame 1
Product Name
type III pantothenate kinase
Product Name Confidence: Class 1
Synonyms
Evidence for Translation
Identified using nanoflow high-pressure liquid chromatography (HPLC) in conjunction with microelectrospray ionization on LTQ XL mass spectrometer (PMID:24291602).
Charge (pH 7) -4.28
Kyte-Doolittle Hydrophobicity Value 0.199
Molecular Weight (kDa) 26.8
Isoelectric Point (pI) 5.37

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

PDB 3D Structures

Accession Header Accession Date Compound Source Resolution Method Percent Identity
2F9W TRANSFERASE 12/06/05 Structure of the type III CoaA from Pseudomonas aeruginosa Pseudomonas aeruginosa 1.9 X-RAY DIFFRACTION 100.0
2F9T TRANSFERASE 12/06/05 Structure of the type III CoaA from Pseudomonas aeruginosa Pseudomonas aeruginosa 2.2 X-RAY DIFFRACTION 100.0

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 316 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG001432 (525 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA4279

Human Homologs

References

Identification of a Bordetella pertussis regulatory factor required for transcription of the pertussis toxin operon in Escherichia coli.
DeShazer D, Wood GE, Friedman RL
J Bacteriol 1995 Jul;177(13):3801-7
PubMed ID: 7601846
Prokaryotic type II and type III pantothenate kinases: The same monomer fold creates dimers with distinct catalytic properties.
Hong BS, Yun MK, Zhang YM, Chohnan S, Rock CO, White SW, Jackowski S, Park HW, Leonardi R
Structure 2006 Aug;14(8):1251-61
PubMed ID: 16905099