Pseudomonas aeruginosa PAO1, PA4482 (gatC)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse PseudoCyc / Metabolic Pathways

Gene Feature Overview

Strain Pseudomonas aeruginosa PAO1 (Stover et al., 2000)
GCF_000006765.1|latest
Locus Tag
PA4482
Name
gatC
Replicon chromosome
Genomic location 5013671 - 5013961 (+ strand)

Cross-References

RefSeq NP_253172.1
GI 15599678
Affymetrix PA4482_gatC_at
Entrez 881166
GenBank AAG07870.1
INSDC AAG07870.1
NCBI Locus Tag PA4482
protein_id(GenBank) gb|AAG07870.1|AE004862_4|gnl|PseudoCAP|PA4482
TIGR NTL03PA04483
UniParc UPI000012B184
UniProtKB Acc Q9HVT9
UniProtKB ID GATC_PSEAE
UniRef100 UniRef100_Q9HVT9
UniRef50 UniRef50_Q9HVT9
UniRef90 UniRef90_Q9HVT9

Product

Feature Type CDS
Coding Frame 1
Product Name
Glu-tRNA(Gln) amidotransferase subunit C
Product Name Confidence: Class 2
Synonyms
Evidence for Translation
Identified using nanoflow high-pressure liquid chromatography (HPLC) in conjunction with microelectrospray ionization on LTQ XL mass spectrometer (PMID:24291602).
Charge (pH 7) -8.29
Kyte-Doolittle Hydrophobicity Value -0.235
Molecular Weight (kDa) 10.5
Isoelectric Point (pI) 4.30

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

PDB 3D Structures

Accession Header Accession Date Compound Source Resolution Method Percent Identity
4WJ3 LIGASE/RNA 09/29/14 Crystal structure of the asparagine transamidosome from Pseudomonas aeruginosa Pseudomonas aeruginosa PAO1; SYNTHETIC CONSTRUCT 3.705 X-RAY DIFFRACTION 100.0

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 413 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG004071 (536 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA4482
Search term: gatC

Human Homologs

References

Glu-tRNAGln amidotransferase: a novel heterotrimeric enzyme required for correct decoding of glutamine codons during translation.
Curnow AW, Hong Kw, Yuan R, Kim Si, Martins O, Winkler W, Henkin TM, Söll D
Proc Natl Acad Sci U S A 1997 Oct 28;94(22):11819-26
PubMed ID: 9342321