Pseudomonas aeruginosa PAO1, PA4522 (ampD)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse PseudoCyc / Metabolic Pathways

Gene Feature Overview

Strain Pseudomonas aeruginosa PAO1 (Stover et al., 2000)
GCF_000006765.1|latest
Locus Tag
PA4522
Name
ampD
Replicon chromosome
Genomic location 5064774 - 5065340 (- strand)
Transposon Mutants 2 transposon mutants in PAO1
Transposon Mutants in orthologs 1 transposon mutants in orthologs

Cross-References

RefSeq NP_253212.1
GI 15599718
Affymetrix PA4522_ampD_at
DNASU PaCD00007955
Entrez 881105
GenBank AAG07910.1
INSDC AAG07910.1
NCBI Locus Tag PA4522
protein_id(GenBank) gb|AAG07910.1|AE004866_4|gnl|PseudoCAP|PA4522
TIGR NTL03PA04523
UniParc UPI00000D421E
UniProtKB Acc G3XCW9
UniProtKB ID G3XCW9_PSEAE
UniRef100 UniRef100_G3XCW9
UniRef50 UniRef50_P82974
UniRef90 UniRef90_G3XCW9

Product

Feature Type CDS
Coding Frame 1
Product Name
beta-lactamase expression regulator AmpD
Product Name Confidence: Class 2
Synonyms
Evidence for Translation
Charge (pH 7) -6.99
Kyte-Doolittle Hydrophobicity Value -0.447
Molecular Weight (kDa) 21.0
Isoelectric Point (pI) 5.50

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 242 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG004102 (487 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA4522
Search term: ampD

Human Homologs

References

Escherichia coli contains a set of genes homologous to those involved in protein secretion, DNA uptake and the assembly of type-4 fimbriae in other bacteria.
Whitchurch CB, Mattick JS
Gene 1994 Dec 2;150(1):9-15
PubMed ID: 7959070