Pseudomonas aeruginosa PAO1, PA4538 (ndh)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse PseudoCyc / Metabolic Pathways

Gene Feature Overview

Strain Pseudomonas aeruginosa PAO1 (Stover et al., 2000)
GCF_000006765.1|latest
Locus Tag
PA4538
Name
ndh
Replicon chromosome
Genomic location 5077770 - 5079077 (+ strand)
Transposon Mutants 2 transposon mutants in PAO1
Transposon Mutants in orthologs 1 transposon mutants in orthologs

Cross-References

RefSeq NP_253228.1
GI 15599734
Affymetrix PA4538_ndh_at
Entrez 878460
GenBank AAG07926.1
INSDC AAG07926.1
NCBI Locus Tag PA4538
protein_id(GenBank) gb|AAG07926.1|AE004867_12|gnl|PseudoCAP|PA4538
TIGR NTL03PA04539
UniParc UPI00000C5D59
UniProtKB Acc Q9HVN9
UniProtKB ID Q9HVN9_PSEAE
UniRef100 UniRef100_W0Z586
UniRef50 UniRef50_C5ATR0
UniRef90 UniRef90_A6VBS4

Product

Feature Type CDS
Coding Frame 1
Product Name
NADH dehydrogenase
Product Name Confidence: Class 2
Synonyms
Evidence for Translation
Identified using nanoflow high-pressure liquid chromatography (HPLC) in conjunction with microelectrospray ionization on LTQ XL mass spectrometer (PMID:24291602).
Charge (pH 7) 5.76
Kyte-Doolittle Hydrophobicity Value -0.121
Molecular Weight (kDa) 47.4
Isoelectric Point (pI) 8.47

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Membrane Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 487 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG004118 (534 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA4538
Search term: ndh

Human Homologs

References

In vitro synthesis of the respiratory NADH dehydrogenase of Escherichia coli. Role of UUG as initiation codon.
Poulis MI, Shaw DC, Campbell HD, Young IG
Biochemistry 1981 Jul 7;20(14):4178-85
PubMed ID: 7025892