Strain |
Pseudomonas aeruginosa PAO1 (Stover et al., 2000)
GCF_000006765.1|latest |
Locus Tag |
PA4728
|
Name |
folK
|
Replicon | chromosome |
Genomic location | 5310726 - 5311214 (+ strand) |
Transposon Mutants in orthologs | 2 transposon mutants in orthologs |
RefSeq | NP_253416.1 |
GI | 15599922 |
Affymetrix | PA4728_folK_at |
DNASU | PaCD00008052 |
Entrez | 881616 |
GenBank | AAG08114.1 |
INSDC | AAG08114.1 |
NCBI Locus Tag | PA4728 |
protein_id(GenBank) | gb|AAG08114.1|AE004886_6|gnl|PseudoCAP|PA4728 |
TIGR | NTL03PA04729 |
UniParc | UPI00000C5DE4 |
UniProtKB Acc | Q9HV71 |
UniProtKB ID | HPPK_PSEAE |
UniRef100 | UniRef100_Q9HV71 |
UniRef50 | UniRef50_P43777 |
UniRef90 | UniRef90_Q9HV71 |
Feature Type | CDS |
Coding Frame | 1 |
Product Name |
2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
|
Synonyms |
7,8-dihydro-6-hydroxymethylpterin pyrophosphokinase 6-hydroxymethyl-7,8-dihydropterin pyrophosphokinase |
Evidence for Translation |
Identified using nanoflow high-pressure liquid chromatography (HPLC) in conjunction with microelectrospray ionization on LTQ XL mass spectrometer (PMID:24291602).
|
Charge (pH 7) | -7.31 |
Kyte-Doolittle Hydrophobicity Value | 0.035 |
Molecular Weight (kDa) | 18.0 |
Isoelectric Point (pI) | 4.56 |
Individual Mappings | |
Additional evidence for subcellular localization |
Results |
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 547 genera
|
Pseudomonas Ortholog Database | View orthologs at Pseudomonas Ortholog Database |
Pseudomonas Ortholog Group |
POG004375 (535 members) |
Putative Inparalogs | None Found |
STRING database | Search for predicted protein-protein interactions using:
Search term: PA4728
Search term: folK
|
Genetics and sequence analysis of the pcnB locus, an Escherichia coli gene involved in plasmid copy number control.
Liu JD, Parkinson JS
J Bacteriol 1989 Mar;171(3):1254-61
PubMed ID: 2537812
|
Cloning, sequence analysis, and overexpression of Escherichia coli folK, the gene coding for 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase.
Talarico TL, Ray PH, Dev IK, Merrill BM, Dallas WS
J Bacteriol 1992 Sep;174(18):5971-7
PubMed ID: 1325970
|