Strain |
Pseudomonas aeruginosa PAO1 (Stover et al., 2000)
GCF_000006765.1|latest |
Locus Tag |
PA4729
|
Name |
panB
|
Replicon | chromosome |
Genomic location | 5311464 - 5312264 (+ strand) |
Transposon Mutants | 1 transposon mutants in PAO1 |
Transposon Mutants in orthologs | 2 transposon mutants in orthologs |
RefSeq | NP_253417.1 |
GI | 15599923 |
Affymetrix | PA4729_panB_at |
DNASU | PaCD00008053 |
Entrez | 881621 |
GenBank | AAG08115.1 |
INSDC | AAG08115.1 |
NCBI Locus Tag | PA4729 |
protein_id(GenBank) | gb|AAG08115.1|AE004886_7|gnl|PseudoCAP|PA4729 |
TIGR | NTL03PA04730 |
UniParc | UPI0000131262 |
UniProtKB Acc | Q9HV70 |
UniProtKB ID | PANB2_PSEAE |
UniRef100 | UniRef100_Q9HV70 |
UniRef50 | UniRef50_Q9JZW6 |
UniRef90 | UniRef90_Q9HV70 |
Feature Type | CDS |
Coding Frame | 1 |
Product Name |
3-methyl-2-oxobutanoate hydroxymethyltransferase
|
Synonyms |
alpha-ketoisovalerate hydroxymethyltransferase ketopantoate hydroxymethyltransferase |
Evidence for Translation |
Identified using nanoflow high-pressure liquid chromatography (HPLC) in conjunction with microelectrospray ionization on LTQ XL mass spectrometer (PMID:24291602).
Detected by MALDI-TOF/TOF (PMID:19333994).
|
Charge (pH 7) | -5.20 |
Kyte-Doolittle Hydrophobicity Value | 0.271 |
Molecular Weight (kDa) | 27.9 |
Isoelectric Point (pI) | 5.82 |
Individual Mappings | |
Additional evidence for subcellular localization |
Results |
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 533 genera
|
Pseudomonas Ortholog Database | View orthologs at Pseudomonas Ortholog Database |
Pseudomonas Ortholog Group |
POG004376 (536 members) |
Putative Inparalogs | None Found |
STRING database | Search for predicted protein-protein interactions using:
Search term: PA4729
Search term: panB
Search term: 3-methyl-2-oxobutanoate hydroxymethyltransferase
|
Cloning and sequencing of the Escherichia coli panB gene, which encodes ketopantoate hydroxymethyltransferase, and overexpression of the enzyme.
Jones CE, Brook JM, Buck D, Abell C, Smith AG
J Bacteriol 1993 Apr;175(7):2125-30
PubMed ID: 8096212
|
Analysis of the periplasmic proteome of Pseudomonas aeruginosa, a metabolically versatile opportunistic pathogen.
Imperi F, Ciccosanti F, Perdomo AB, Tiburzi F, Mancone C, Alonzi T, Ascenzi P, Piacentini M, Visca P, Fimia GM
Proteomics 2009 Apr;9(7):1901-15
PubMed ID: 19333994
|