Strain |
Pseudomonas aeruginosa PAO1 (Stover et al., 2000)
GCF_000006765.1|latest |
Locus Tag |
PA4848
|
Name |
accC
|
Replicon | chromosome |
Genomic location | 5442792 - 5444141 (+ strand) |
RefSeq | NP_253535.1 |
GI | 15600041 |
Affymetrix | PA4848_accC_at |
Entrez | 879558 |
GenBank | AAG08233.1 |
INSDC | AAG08233.1 |
NCBI Locus Tag | PA4848 |
protein_id(GenBank) | gb|AAG08233.1|AE004898_4|gnl|PseudoCAP|PA4848 |
TIGR | NTL03PA04849 |
UniParc | UPI00001251AF |
UniProtKB Acc | P37798 |
UniProtKB ID | ACCC_PSEAE |
UniRef100 | UniRef100_P37798 |
UniRef50 | UniRef50_P37798 |
UniRef90 | UniRef90_P37798 |
Feature Type | CDS |
Coding Frame | 1 |
Product Name |
biotin carboxylase
|
Synonyms |
acetyl-CoA carboxylase |
Evidence for Translation |
Detected by MALDI-TOF/TOF (PMID:19333994).
Identified using nanoflow high-pressure liquid chromatography (HPLC) in conjunction with microelectrospray ionization on LTQ XL mass spectrometer (PMID:24291602).
|
Charge (pH 7) | -5.82 |
Kyte-Doolittle Hydrophobicity Value | -0.183 |
Molecular Weight (kDa) | 48.9 |
Isoelectric Point (pI) | 6.28 |
Individual Mappings | |
Additional evidence for subcellular localization |
Accession | Header | Accession Date | Compound | Source | Resolution | Method | Percent Identity |
2C00 | LIGASE | 03/21/08 | Crystal Structure of Biotin Carboxylase from Pseudomonas aeruginosa in apo form | PSEUDOMONAS AERUGINOSA | 2.5 | X-RAY DIFFRACTION | 100.0 |
2VQD | LIGASE | 03/13/08 | Crystal Structure of Biotin Carboxylase from Pseudomonas aeruginosa complexed with AMPCP | PSEUDOMONAS AERUGINOSA | 2.41 | X-RAY DIFFRACTION | 100.0 |
Results |
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 630 genera
|
Pseudomonas Ortholog Database | View orthologs at Pseudomonas Ortholog Database |
Pseudomonas Ortholog Group |
POG004477 (535 members) |
Putative Inparalogs | None Found |
STRING database | Search for predicted protein-protein interactions using:
Search term: PA4848
Search term: accC
Search term: biotin carboxylase
|
Ensembl
110, assembly
GRCh38.p14
|
propionyl-CoA carboxylase subunit alpha [Source:HGNC Symbol;Acc:HGNC:8653]
E-value:
5.0e-120
Percent Identity:
47.5
|
Ensembl
110, assembly
GRCh38.p14
|
propionyl-CoA carboxylase subunit alpha [Source:HGNC Symbol;Acc:HGNC:8653]
E-value:
5.0e-120
Percent Identity:
47.5
|
Ensembl
110, assembly
GRCh38.p14
|
propionyl-CoA carboxylase subunit alpha [Source:HGNC Symbol;Acc:HGNC:8653]
E-value:
5.0e-120
Percent Identity:
47.5
|
Acetyl-CoA carboxylase from Escherichia coli: gene organization and nucleotide sequence of the biotin carboxylase subunit.
Kondo H, Shiratsuchi K, Yoshimoto T, Masuda T, Kitazono A, Tsuru D, Anai M, Sekiguchi M, Tanabe T
Proc Natl Acad Sci U S A 1991 Nov 1;88(21):9730-3
PubMed ID: 1682920
|
Analysis of the periplasmic proteome of Pseudomonas aeruginosa, a metabolically versatile opportunistic pathogen.
Imperi F, Ciccosanti F, Perdomo AB, Tiburzi F, Mancone C, Alonzi T, Ascenzi P, Piacentini M, Visca P, Fimia GM
Proteomics 2009 Apr;9(7):1901-15
PubMed ID: 19333994
|