Strain |
Pseudomonas aeruginosa PAO1 (Stover et al., 2000)
GCF_000006765.1|latest |
Locus Tag |
PA4855
|
Name |
purD
|
Replicon | chromosome |
Genomic location | 5450757 - 5452046 (+ strand) |
Transposon Mutants | 3 transposon mutants in PAO1 |
Transposon Mutants in orthologs | 1 transposon mutants in orthologs |
RefSeq | NP_253542.1 |
GI | 15600048 |
Affymetrix | PA4855_purD_at |
Entrez | 878236 |
GenBank | AAG08240.1 |
INSDC | AAG08240.1 |
NCBI Locus Tag | PA4855 |
protein_id(GenBank) | gb|AAG08240.1|AE004899_1|gnl|PseudoCAP|PA4855 |
TIGR | NTL03PA04856 |
UniParc | UPI0000132A37 |
UniProtKB Acc | Q9HUV8 |
UniProtKB ID | PUR2_PSEAE |
UniRef100 | UniRef100_Q9HUV8 |
UniRef50 | UniRef50_P26977 |
UniRef90 | UniRef90_Q9HUV8 |
Feature Type | CDS |
Coding Frame | 1 |
Product Name |
phosphoribosylamine--glycine ligase
|
Synonyms |
phosphoribosylglycineamide synthetase |
Evidence for Translation |
Detected by MALDI-TOF/TOF (PMID:19333994).
Identified using nanoflow high-pressure liquid chromatography (HPLC) in conjunction with microelectrospray ionization on LTQ XL mass spectrometer (PMID:24291602).
|
Charge (pH 7) | -14.66 |
Kyte-Doolittle Hydrophobicity Value | 0.057 |
Molecular Weight (kDa) | 45.2 |
Isoelectric Point (pI) | 4.68 |
Individual Mappings | |
Additional evidence for subcellular localization |
Source 1 | |
Database | Victors : 4217 |
Category | |
Evidence |
ECO:0000315
mutant phenotype evidence used in manual assertion
|
Host Organism | Rattus norvegicus |
Notes | |
Infection model | Rat agar bead model of chronic lung infection |
Reference | 14641575 |
Results |
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 627 genera
|
Pseudomonas Ortholog Database | View orthologs at Pseudomonas Ortholog Database |
Pseudomonas Ortholog Group |
POG004484 (536 members) |
Putative Inparalogs | None Found |
STRING database | Search for predicted protein-protein interactions using:
Search term: PA4855
Search term: purD
Search term: phosphoribosylamine--glycine ligase
|
Ensembl
110, assembly
GRCh38.p14
|
phosphoribosylglycinamide formyltransferase, phosphoribosylglycinamide synthetase, phosphoribosylaminoimidazole synthetase [Source:HGNC Symbol;Acc:HGNC:4163]
E-value:
3.6e-115
Percent Identity:
52.8
|
Ensembl
110, assembly
GRCh38.p14
|
phosphoribosylglycinamide formyltransferase, phosphoribosylglycinamide synthetase, phosphoribosylaminoimidazole synthetase [Source:HGNC Symbol;Acc:HGNC:4163]
E-value:
3.6e-115
Percent Identity:
52.8
|
Ensembl
110, assembly
GRCh38.p14
|
phosphoribosylglycinamide formyltransferase, phosphoribosylglycinamide synthetase, phosphoribosylaminoimidazole synthetase [Source:HGNC Symbol;Acc:HGNC:4163]
E-value:
3.6e-115
Percent Identity:
52.8
|
Ensembl
110, assembly
GRCh38.p14
|
phosphoribosylglycinamide formyltransferase, phosphoribosylglycinamide synthetase, phosphoribosylaminoimidazole synthetase [Source:HGNC Symbol;Acc:HGNC:4163]
E-value:
3.6e-115
Percent Identity:
52.8
|
Glycinamide ribonucleotide synthetase from Escherichia coli: cloning, overproduction, sequencing, isolation, and characterization.
Cheng YS, Shen Y, Rudolph J, Stern M, Stubbe J, Flannigan KA, Smith JM
Biochemistry 1990 Jan 9;29(1):218-27
PubMed ID: 2182115
|
Analysis of the periplasmic proteome of Pseudomonas aeruginosa, a metabolically versatile opportunistic pathogen.
Imperi F, Ciccosanti F, Perdomo AB, Tiburzi F, Mancone C, Alonzi T, Ascenzi P, Piacentini M, Visca P, Fimia GM
Proteomics 2009 Apr;9(7):1901-15
PubMed ID: 19333994
|