Pseudomonas aeruginosa PAO1, PA4867 (ureB)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse PseudoCyc / Metabolic Pathways

Gene Feature Overview

Strain Pseudomonas aeruginosa PAO1 (Stover et al., 2000)
GCF_000006765.1|latest
Locus Tag
PA4867
Name
ureB
Replicon chromosome
Genomic location 5464453 - 5464758 (+ strand)
Transposon Mutants in orthologs 1 transposon mutants in orthologs

Cross-References

RefSeq NP_253554.1
GI 15600060
Affymetrix PA4867_ureB_at
Entrez 882185
GenBank AAG08252.1
INSDC AAG08252.1
NCBI Locus Tag PA4867
protein_id(GenBank) gb|AAG08252.1|AE004900_6|gnl|PseudoCAP|PA4867
TIGR NTL03PA04868
UniParc UPI00000C5E49
UniProtKB Acc Q9HUU6
UniProtKB ID URE2_PSEAE
UniRef100 UniRef100_B7V1T0
UniRef50 UniRef50_A1TSZ5
UniRef90 UniRef90_B7V1T0

Product

Feature Type CDS
Coding Frame 1
Product Name
urease beta subunit
Product Name Confidence: Class 2
Synonyms
Evidence for Translation
Charge (pH 7) -1.53
Kyte-Doolittle Hydrophobicity Value -0.235
Molecular Weight (kDa) 11.0
Isoelectric Point (pI) 5.69

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 238 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG004495 (525 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA4867
Search term: ureB

Human Homologs

References

Characterization of a plasmid-encoded urease gene cluster found in members of the family Enterobacteriaceae.
D'Orazio SE, Collins CM
J Bacteriol 1993 Mar;175(6):1860-4
PubMed ID: 8449894