Pseudomonas aeruginosa PAO1, PA5083 (dguB)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse PseudoCyc / Metabolic Pathways

Gene Feature Overview

Strain Pseudomonas aeruginosa PAO1 (Stover et al., 2000)
GCF_000006765.1|latest
Locus Tag
PA5083
Name
dguB
Replicon chromosome
Genomic location 5721892 - 5722242 (- strand)
Transposon Mutants 1 transposon mutants in PAO1
Transposon Mutants in orthologs 3 transposon mutants in orthologs

Cross-References

RefSeq NP_253770.1
GI 15600276
Affymetrix PA5083_at
DNASU PaCD00008187
Entrez 880265
GenBank AAG08468.1
INSDC AAG08468.1
NCBI Locus Tag PA5083
protein_id(GenBank) gb|AAG08468.1|AE004921_5|gnl|PseudoCAP|PA5083
TIGR NTL03PA05084
UniParc UPI00000C5EF1
UniProtKB Acc Q9HUA0
UniProtKB ID Q9HUA0_PSEAE
UniRef100 UniRef100_Q9HUA0
UniRef50 UniRef50_Q4KIK0
UniRef90 UniRef90_Q9HUA0

Product

Feature Type CDS
Coding Frame 1
Product Name
Rid2 subfamily protein
Product Name Confidence: Class 1
Synonyms DguB
Evidence for Translation
Identified using nanoflow high-pressure liquid chromatography (HPLC) in conjunction with microelectrospray ionization on LTQ XL mass spectrometer (PMID:24291602).
Charge (pH 7) -1.80
Kyte-Doolittle Hydrophobicity Value 0.063
Molecular Weight (kDa) 12.6
Isoelectric Point (pI) 5.13

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 423 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG001525 (1734 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA5083
Search term: dguB

Human Homologs

References

Functional characterization of the dguRABC locus for D-Glu and d-Gln utilization in Pseudomonas aeruginosa PAO1.
He W, Li G, Yang CK, Lu CD
Microbiology (Reading) 2014 Oct;160(Pt 10):2331-2340
PubMed ID: 25082951
Members of the Rid protein family have broad imine deaminase activity and can accelerate the Pseudomonas aeruginosa D-arginine dehydrogenase (DauA) reaction in vitro.
Hodge-Hanson KM, Downs DM
PLoS One 2017;12(9):e0185544
PubMed ID: 28957411