Pseudomonas aeruginosa PAO1, PA5287 (amtB)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse PseudoCyc / Metabolic Pathways

Gene Feature Overview

Strain Pseudomonas aeruginosa PAO1 (Stover et al., 2000)
GCF_000006765.1|latest
Locus Tag
PA5287
Name
amtB
Replicon chromosome
Genomic location 5951115 - 5952443 (- strand)
Transposon Mutants 3 transposon mutants in PAO1
Transposon Mutants in orthologs 2 transposon mutants in orthologs

Cross-References

RefSeq NP_253974.1
GI 15600480
Affymetrix PA5287_amtB_at
Entrez 879509
GenBank AAG08672.1
INSDC AAG08672.1
NCBI Locus Tag PA5287
protein_id(GenBank) gb|AAG08672.1|AE004941_5|gnl|PseudoCAP|PA5287
TIGR NTL03PA05288
UniParc UPI00000C5F8B
UniProtKB Acc Q9HTR7
UniProtKB ID Q9HTR7_PSEAE
UniRef100 UniRef100_Q9HTR7
UniRef50 UniRef50_B6JAH3
UniRef90 UniRef90_Q9HTR7

Product

Feature Type CDS
Coding Frame 1
Product Name
ammonium transporter AmtB
Product Name Confidence: Class 2
Synonyms
Evidence for Translation
Charge (pH 7) -4.66
Kyte-Doolittle Hydrophobicity Value 0.927
Molecular Weight (kDa) 45.8
Isoelectric Point (pI) 5.58

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Membrane Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 533 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG004864 (529 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA5287
Search term: amtB

Human Homologs

References

Genome-wide identification of Pseudomonas aeruginosa exported proteins using a consensus computational strategy combined with a laboratory-based PhoA fusion screen.
Lewenza S, Gardy JL, Brinkman FS, Hancock RE
Genome Res 2005 Feb;15(2):321-9
PubMed ID: 15687295
Characterization of the glnK-amtB operon of Azotobacter vinelandii.
Meletzus D, Rudnick P, Doetsch N, Green A, Kennedy C
J Bacteriol 1998 Jun;180(12):3260-4
PubMed ID: 9620984