Pseudomonas aeruginosa PAO1, PA5355 (glcD)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse PseudoCyc / Metabolic Pathways

Gene Feature Overview

Strain Pseudomonas aeruginosa PAO1 (Stover et al., 2000)
GCF_000006765.1|latest
Locus Tag
PA5355
Name
glcD
Replicon chromosome
Genomic location 6022203 - 6023702 (- strand)
Transposon Mutants 3 transposon mutants in PAO1
Transposon Mutants in orthologs 2 transposon mutants in orthologs

Cross-References

RefSeq NP_254042.1
GI 15600548
Affymetrix PA5355_glcD_at
Entrez 881631
GenBank AAG08740.1
INSDC AAG08740.1
NCBI Locus Tag PA5355
protein_id(GenBank) gb|AAG08740.1|AE004947_10|gnl|PseudoCAP|PA5355
TIGR NTL03PA05356
UniParc UPI00000C5FBE
UniProtKB Acc Q9HTK3
UniProtKB ID Q9HTK3_PSEAE
UniRef100 UniRef100_Q9HTK3
UniRef50 UniRef50_P0AEQ0
UniRef90 UniRef90_Q9HTK3

Product

Feature Type CDS
Coding Frame 1
Product Name
glycolate oxidase subunit GlcD
Product Name Confidence: Class 2
Synonyms
Evidence for Translation
Identified using nanoflow high-pressure liquid chromatography (HPLC) in conjunction with microelectrospray ionization on LTQ XL mass spectrometer (PMID:24291602).
Charge (pH 7) -17.46
Kyte-Doolittle Hydrophobicity Value 0.102
Molecular Weight (kDa) 53.7
Isoelectric Point (pI) 5.06

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 548 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG004921 (478 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA5355
Search term: glcD

Human Homologs

References

Cross-induction of glc and ace operons of Escherichia coli attributable to pathway intersection. Characterization of the glc promoter.
Pellicer MT, Fernandez C, Badía J, Aguilar J, Lin EC, Baldom L
J Biol Chem 1999 Jan 15;274(3):1745-52
PubMed ID: 9880556