Pseudomonas aeruginosa PAO1, PA5379 (sdaB)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse PseudoCyc / Metabolic Pathways

Gene Feature Overview

Strain Pseudomonas aeruginosa PAO1 (Stover et al., 2000)
GCF_000006765.1|latest
Locus Tag
PA5379
Name
sdaB
Replicon chromosome
Genomic location 6056877 - 6058253 (+ strand)
Transposon Mutants 2 transposon mutants in PAO1
Transposon Mutants in orthologs 4 transposon mutants in orthologs

Cross-References

RefSeq NP_254066.1
GI 15600572
Affymetrix PA5379_sdaB_at
Entrez 878445
GenBank AAG08764.1
INSDC AAG08764.1
NCBI Locus Tag PA5379
protein_id(GenBank) gb|AAG08764.1|AE004950_7|gnl|PseudoCAP|PA5379
TIGR NTL03PA05380
UniParc UPI00000C5FD0
UniProtKB Acc Q9HTI5
UniProtKB ID Q9HTI5_PSEAE
UniRef100 UniRef100_Q9HTI5
UniRef50 UniRef50_O86564
UniRef90 UniRef90_A6VEJ1

Product

Feature Type CDS
Coding Frame 1
Product Name
L-serine dehydratase
Product Name Confidence: Class 2
Synonyms L-serine deaminase
Evidence for Translation
Charge (pH 7) -7.58
Kyte-Doolittle Hydrophobicity Value -0.005
Molecular Weight (kDa) 49.2
Isoelectric Point (pI) 5.80

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 361 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG003095 (985 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA5379
Search term: sdaB

Human Homologs

References

L-serine degradation in Escherichia coli K-12: cloning and sequencing of the sdaA gene.
Su HS, Lang BF, Newman EB
J Bacteriol 1989 Sep;171(9):5095-102
PubMed ID: 2504697
Use of gene fusions of the structural gene sdaA to purify L-serine deaminase 1 from Escherichia coli K-12.
Su H, Moniakis J, Newman EB
Eur J Biochem 1993 Feb 1;211(3):521-7
PubMed ID: 8436113