Pseudomonas aeruginosa PAO1, PA5538 (amiA)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse PseudoCyc / Metabolic Pathways

Gene Feature Overview

Strain Pseudomonas aeruginosa PAO1 (Stover et al., 2000)
GCF_000006765.1|latest
Locus Tag
PA5538
Name
amiA
Replicon chromosome
Genomic location 6230369 - 6231562 (- strand)
Transposon Mutants 2 transposon mutants in PAO1
Transposon Mutants in orthologs 1 transposon mutants in orthologs

Cross-References

RefSeq NP_254225.1
GI 15600731
Affymetrix PA5538_amiA_at
Entrez 877724
GenBank AAG08923.1
INSDC AAG08923.1
NCBI Locus Tag PA5538
protein_id(GenBank) gb|AAG08923.1|AE004966_5|gnl|PseudoCAP|PA5538
TIGR NTL03PA05539
UniParc UPI00000C6060
UniProtKB Acc Q9HT36
UniProtKB ID Q9HT36_PSEAE
UniRef100 UniRef100_W0Z2Y2
UniRef50 UniRef50_Q4K3E9
UniRef90 UniRef90_Q02DH0

Product

Feature Type CDS
Coding Frame 1
Product Name
N-acetylmuramoyl-L-alanine amidase
Product Name Confidence: Class 2
Synonyms
Evidence for Translation
Charge (pH 7) 16.66
Kyte-Doolittle Hydrophobicity Value -0.155
Molecular Weight (kDa) 42.9
Isoelectric Point (pI) 10.96

Subcellular localization

Individual Mappings
Localization Confidence PMID
Unknown Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 466 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG005071 (402 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA5538
Search term: amiA

Human Homologs

References

Genome-wide identification of Pseudomonas aeruginosa exported proteins using a consensus computational strategy combined with a laboratory-based PhoA fusion screen.
Lewenza S, Gardy JL, Brinkman FS, Hancock RE
Genome Res 2005 Feb;15(2):321-9
PubMed ID: 15687295
The mutL repair gene of Escherichia coli K-12 forms a superoperon with a gene encoding a new cell-wall amidase.
Tsui HC, Zhao G, Feng G, Leung HC, Winkler ME
Mol Microbiol 1994 Jan;11(1):189-202
PubMed ID: 7511774