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               PA0019               
Key to diagram


View in GBrowse: 16 putative orthologs View metabolic pathways using PseudoCyc Acknowledgements for this annotation
Gene Information
Strain Pseudomonas aeruginosa PAO1 (Tax ID: 208964) Replicon Chromosome(5651 genes, 6264404 bp) [ RefSeq ]
Gene name def  Alternate Gene Names
Locus tag PA0019 (View 6 updates) Submit an Update GenBank Identifier (GI) 15595217 (Precomputed BLAST results at BLINK )
Genomic location 21573 - 21067 (-) Feature type CDS 
Transposon Mutant Available?Transposon mutant library help No transposon mutant available yet Pseudomonas Ortholog Group Explanation of Orthologous Groups
Product Information
Product Name polypeptide deformylase (Class 2  Explanation of Product Name Confidence)
Alternate Product Names formylmethionine deformylase
Subcellular localization
Cytoplasmic (Class 3Explanation of Localization Confidence)
Alternate Annotations and Cross-References
TIGR NTL03PA00020
Systomonas PA0019
RefSeq NP_248709.1
GI 15595217
KEGG PA0019
GBrowse Click here for a GBrowse View of this and other annotations.
PseudoCyc Click here to view metabolic pathways in PseudoCyc.
Function Classification / Gene Ontology (GO)
PseudoCAP Function Class Translation, post-translational modification, degradation
GO Accession GO Term Evidence
Molecular Function
GO:0008463 formylmethionine deformylase activity RCA
GO:0042586 peptide deformylase activity IEA
Biological Process
GO:0044267 cellular protein metabolic process ISS
GO:0006464 protein modification process IEA
Cellular Component
COG PredictionExplanation of COG predictions
Accession Description Category
COG0242 Def, N-formylmethionyl-tRNA deformylase [Translation, ribosomal structure and biogenesis]. Translation, ribosomal structure and biogenesis
Homology
BLINK Precomputed BLAST results at BLINK
Homologs Explanation of Homologs Field 75% similar to E. coli polypeptide deformylase.
Most Similar Human Homolog
ENSP00000288022, Percent Identity: 32.73%, E-Value: 2e-15, Ensembl Release: 56.
Description: Conserved oligomeric Golgi complex subunit 8
Structure Features
PFAM predictions Explanation of PFAM predictions
Accession Domain Start Stop E-value Release No.
PF01327 Pep_deformylase, Polypeptide deformylase. 3 153 2e-50 23.0
 
Microarray Expression Data
NCBI GEO Link
Upstream 500 BP Region TTGATCTTGTCCAGCGGGATGGTCGGGATGGCCTCGGCGATCGGCGTGCTGCGGATCTTCGGCGACAGCTTGATGGTCCCGCGCGATTCGCCACGGTTCA GCACCAGGCGCGGCTGGCCATCGACGTAGACCAGGCTGAGGGTGTCGCCGGGGTAGATCAGGTGGGGATTCTGGATCTGCGGGTTGGCGTGCCAGAGTTC CGGCCACTTCCATGGCTGGCGGAGGAATTTCCCCGAGATGTCCCACAGGGTATCGCCCCTGACCACCGTGTAGCGGTCCGGATGCCCTTCCCTGAGGTCG ACCTGGGCCTGCGCCAGACCGCTCGCGGCAAGGAGCAGAAGGGCGACTAGTGATTTCCTCATGCAGTGAATCCCTTTATCATGTCGACATACGCGAAACG CCCGAAGCCCGCGAGAAACGCGGTCTGAAGCCGTTTTCAAGCTGCGCGCCATCTTAGCAGCGGATTTTCAATCGATTCCACAAGTGCATCACAAACGCAT

BLAST search against this genome or other genomes in database
Need more than 500 BP? Try our sequence retrieval tool or view intergenic regions in GBrowse.

DNA Sequence ATGGCCATCCTGAACATTCTCGAATTCCCCGATCCGCGCCTGCGGACCATCGCCAAACCGGTGGAGGTGGTCGACGACGCGGTGCGCCAGCTGATCGACG ACATGTTCGAAACCATGTACGAAGCCCCGGGCATCGGCCTCGCCGCGACCCAGGTGAACGTGCACAAGCGCATCGTGGTCATGGACCTCAGCGAAGACAA GTCCGAGCCGAGGGTATTCATCAACCCCGAGTTCGAACCGCTGACCGAGGATATGGACCAGTACCAGGAAGGCTGCCTGTCGGTACCCGGCTTCTACGAG AACGTGGACCGACCGCAGAAGGTCCGGATCAAGGCCCTCGACCGCGATGGCAACCCCTTCGAGGAAGTCGCCGAAGGCCTGCTGGCGGTATGCATCCAGC ACGAATGCGACCACCTCAACGGCAAGCTGTTCGTCGACTACCTGTCCACCCTCAAGCGCGACCGCATCCGCAAGAAGCTGGAAAAGCAGCATCGACAGCA GGCGTGA

BLAST search against this genome or other genomes in database

Downstream 500 BP region Click here to view the nucleotide sequence of the region 500 BP downstream of this gene.
Protein Sequence MAILNILEFPDPRLRTIAKPVEVVDDAVRQLIDDMFETMYEAPGIGLAATQVNVHKRIVVMDLSEDKSEPRVFINPEFEPLTEDMDQYQEGCLSVPGFYE NVDRPQKVRIKALDRDGNPFEEVAEGLLAVCIQHECDHLNGKLFVDYLSTLKRDRIRKKLEKQHRQQA

BLAST search against this genome or other genomes in database
View precomputed BLAST results against all genomes at NCBI BLINK
SNPs NOTE: This feature is currently open to beta-testing. We welcome feedback on how to improve this new resource. Please send any comments to pseudocap-mail@sfu.ca.

Showing SNPs occurring in PA0019 gene of Pseudomonas aeruginosa PAO1, Chromosome (21067 to 21573 bp)


Displaying the first five SNPs out of a total of 22 found in all isolate strains ( View all 22 )
Strain Type Mutation Description Effect Details GBrowse
DNA Protein
Pseudomonas aeruginosa PA7 Transition g.21136G>A
Silent
GAC(Asp) -> GAT(Asp) 		SNP-505359 View
Pseudomonas aeruginosa PA7 Transition g.21149T>C p.Lys142Arg
 Missense
AAG(Lys) -> AGG(Arg) 		SNP-505360 View
Pseudomonas aeruginosa PA7 Transition g.21163G>A
Silent
GAC(Asp) -> GAT(Asp) 		SNP-505361 View
Pseudomonas aeruginosa PA7 Transition g.21169T>C
Silent
GAA(Glu) -> GAG(Glu) 		SNP-505362 View
Pseudomonas aeruginosa PA7 Transition g.21175C>T
Silent
CAG(Gln) -> CAA(Gln) 		SNP-505363 View
Select to view SNPs in a specific strain
SNP Map
PubMed A new subclass of the zinc metalloproteases superfamily revealed by the solution structure of peptide deformylase.
Meinnel T, Blanquet S, Dardel F.
J Mol Biol. 1996 Sep 27;262(3):375-86.
PMID: 8845003
 


We thank Cystic Fibrosis Foundation Therapeutics, Inc. for critical funding support for the Pseudomonas Genome Database. When acknowledging use of the database, please cite the article by Winsor et al. (2009; PMID:18978025) and not the web site URL. Thank you!

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