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               PA0023               
Key to diagram


View in GBrowse: (?) 16 putative orthologs View metabolic pathways using PseudoCyc Acknowledgements for this annotation
Gene Information
Strain Pseudomonas aeruginosa PAO1 (Tax ID: 208964) Replicon Chromosome(5651 genes, 6264404 bp) [ RefSeq ]
Gene name qor  Alternate Gene Names
Locus tag PA0023 (View 5 updates) GenBank Identifier (GI) 15595221 (Precomputed BLAST results at BLINK )
Genomic location 25545 - 24568 (-) Feature type CDS 
Transposon Mutant Available?Transposon mutant library help Yes (View in GBrowse) Pseudomonas Ortholog Group Explanation of Orthologous Groups
Product Information
Product Name quinone oxidoreductase (Class 2  Explanation of Product Name Confidence)
Alternate Product Names NADPH:quinone reductase
Subcellular localization
Cytoplasmic (Class 3Explanation of Localization Confidence)
Function Classification / Gene Ontology (GO)
PseudoCAP Function Class Energy metabolism
GO Accession GO Term Evidence
Molecular Function
GO:0004459 L-lactate dehydrogenase activity ISS
GO:0003960 NADPH:quinone reductase activity RCA
GO:0016655 oxidoreductase activity, acting on NADH or NADPH, quinone or similar compound as acceptor IEA
Biological Process
GO:0006091 generation of precursor metabolites and energy ISS
GO:0008152 metabolic process IEA
Cellular Component
COG PredictionExplanation of COG predictions
Accession Description Category
COG0604 Qor, NADPH:quinone reductase and related Zn-dependent oxidoreductases [Energy production and conversion / General function prediction only]. Energy production and conversion / General function prediction only
Reactions
EC Number 1.6.5.5
Homology
BLINK Precomputed BLAST results at BLINK
Homologs Explanation of Homologs Field 72% similar to quinone oxidoreductase [E. coli]
Most Similar Human Homolog
ENSP00000399805, Percent Identity: 31.82%, E-Value: 2e-25, Ensembl Release: 56.
Description: Quinone oxidoreductase
Structure Features
Structure Features Explanation of Structure Features Field PS01162: Quinone oxidoreductase / zeta-crystallin signature
PFAM predictions Explanation of PFAM predictions
Accession Domain Start Stop E-value Release No.
PF08240 ADH_N, Alcohol dehydrogenase GroES-like domain. 28 109 5e-17 23.0
PF00107 ADH_zinc_N, Zinc-binding dehydrogenase. 141 281 2e-26 23.0
 
Microarray Expression Data
NCBI GEO Link
Sequence data
Upstream 500 BP Region GCACGTGGGGGTTTTCCGGATGGATCACCAGCGACACGCCGAGCGCCTGGAAACCGCGCCCGGCCAGTTCCGGCCGATGGGCGCTGGCCGAGGGCGGCAG GCTATCGCCGAAGACGTGGGAAAAATTCACCCCGCCCTTCTCGATCAATGCGCCGTCGCCGATTACCCGCGTCCGTCCGCCGCCACCGGCCGGACGCTCC CAGGCGTCCTCGGCGAAGCGGGCCTTGCCGTCCTCCGCCTCGAGGGCGGCGCAGATGCGGTCTTGCAGGTCGAGCAGGTAGGTTTTGACAGCGGCGATAC GGTCGGTCACGGAGTTCACCTTGGAGCGGGGAGGCCGCGCGGGGCGCGGGCTGGCGACGAAACGAGGGCGCAAGCATACCACCCTGGATGGGTAGCCGGC GCTTGACGGCCGTCAAGGGGAAGGCTTGGATGAAGGCCTTTACCCAGGGTCGCCCACCCGGCGCGACCGTCCGAAACCCTGACGAAGCAGGAGTTCCAGC

BLAST search against this genome or other genomes in database
Need more than 500 BP? Try our sequence retrieval tool or view intergenic regions in GBrowse.

DNA Sequence ATGGCCAAGCGCATCCAGTTCGCTGCCTACGGCGGCCCCGAAGTCCTCGAATACCGCGACTACCAACCCGCCGAGCCGGGCCCCCGGGAAGTCCGCGTGC GCAATCGCGCCATTGGCCTGAACTTCATCGACACCTACTACCGCAGCGGCCTCTATCCGGCCCCCGGCTTACCCTCGGGACTGGGTAGCGAAGGTGCCGG CGAGGTCGAGGCGGTGGGCAGCGAAGTGACCCGTTTCAAGGTCGGCGACCGCGTCGCCTACGCCACCGGCCCCCTGGGCGCCTACAGCGAACTGCATGTG CTGGCGGAGGAGAAGCTGGTCCACCTGCCCGACGGCATCGACTTCGAACAGGCCGCCGCGGTGATGCTCAAGGGGCTCACCACCCAATACCTGCTGCGCC AGACCTACGAACTGCGGGGCGGCGAAACCATTCTCTTCCATGCCGCCGCGGGCGGCGTGGGCCTGTTCGCCTGCCAATGGGCCAAGGCCCTTGGAGTGCA ACTGATCGGCACCGTCAGCTCGCCGGAAAAGGCGCGCCTGGCCAGGCAGCACGGTGCCTGGGAGACCATCGACTACAGCCACGAGAACGTGGCGCGGCGG GTGCTCGAACTGACCGACGGGAAGAAGTGCCCGGTGGTCTACGACTCGGTGGGCAAGGATACCTGGGAAACCTCGCTGGACTGCGTGGCGCCGCGCGGCT TGCTGGTCAGCTTCGGCAACGCCTCGGGGCCGGTGACCGGGGTCAACCTCGGCATCCTCTCGCAGAAGGGTTCGCTGTACGTGACCCGGCCGACCCTGGG CAGCTACGCCGATACCCCGGAAAAACTCCAGGCGATGGCCGACGAGCTGTTCGGCCTGATCGAGCGCGGCGACATCCGCATCGAGATCAACCAGCGCTTC GCCCTGGCCGAAGCAGCCAGGGCGCATACCGAACTGGCCGCACGGCGAACCACCGGCTCGACCGTACTGTTGCCCTGA

BLAST search against this genome or other genomes in database


Downstream 500 BP region Click here to view the nucleotide sequence of the region 500 BP downstream of this gene.

Protein Sequence MAKRIQFAAYGGPEVLEYRDYQPAEPGPREVRVRNRAIGLNFIDTYYRSGLYPAPGLPSGLGSEGAGEVEAVGSEVTRFKVGDRVAYATGPLGAYSELHV LAEEKLVHLPDGIDFEQAAAVMLKGLTTQYLLRQTYELRGGETILFHAAAGGVGLFACQWAKALGVQLIGTVSSPEKARLARQHGAWETIDYSHENVARR VLELTDGKKCPVVYDSVGKDTWETSLDCVAPRGLLVSFGNASGPVTGVNLGILSQKGSLYVTRPTLGSYADTPEKLQAMADELFGLIERGDIRIEINQRF ALAEAARAHTELAARRTTGSTVLLP

BLAST search against this genome or other genomes in database
View precomputed BLAST results against all genomes at NCBI BLINK
References
PubMed Crystal structure of Escherichia coli QOR quinone oxidoreductase complexed with NADPH.
Thorn JM, Barton JD, Dixon NE, Ollis DL, Edwards KJ.
J Mol Biol. 1995 Jun 16;249(4):785-99.
PMID: 7602590
 
Alternate Annotations and Cross-References
TIGR NTL03PA00024
Systomonas PA0023
RefSeq NP_248713.1
GI 15595221
KEGG PA0023
GBrowse Click here for a GBrowse View of this and other annotations.
PseudoCyc Click here to view metabolic pathways in PseudoCyc.


We thank Cystic Fibrosis Foundation Therapeutics, Inc. for critical funding support for the Pseudomonas Genome Database. When acknowledging use of the database, please cite the article by Winsor et al. (2009; PMID:18978025) and not the web site URL. Thank you!

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