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               PA0366               
Key to diagram


View in GBrowse: (?) 16 putative orthologs View metabolic pathways using PseudoCyc Acknowledgements for this annotation
Gene Information
Strain Pseudomonas aeruginosa PAO1 (Tax ID: 208964) Replicon Chromosome(5651 genes, 6264404 bp) [ RefSeq ]
Gene name   Alternate Gene Names
Locus tag PA0366 (View 6 updates) GenBank Identifier (GI) 15595563 (Precomputed BLAST results at BLINK )
Genomic location 410934 - 409504 (-) Feature type CDS 
Transposon Mutant Available?Transposon mutant library help Yes (View in GBrowse) Pseudomonas Ortholog Group Explanation of Orthologous Groups
Product Information
Product Name probable aldehyde dehydrogenase (Class 3  Explanation of Product Name Confidence)
Alternate Product Names
Subcellular localization
Cytoplasmic (Class 3Explanation of Localization Confidence)
Function Classification / Gene Ontology (GO)
PseudoCAP Function Class Putative enzymes
GO Accession GO Term Evidence
Molecular Function
GO:0016620 oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor IEA
Biological Process
Cellular Component
COG PredictionExplanation of COG predictions
Accession Description Category
COG1012 PutA, NAD-dependent aldehyde dehydrogenases [Energy production and conversion]. Energy production and conversion
Homology
BLINK Precomputed BLAST results at BLINK
Homologs Explanation of Homologs Field 62% similar to calB of [Pseudomonas sp.]
Most Similar Human Homolog
ENSP00000385699, Percent Identity: 38.68%, E-Value: 8e-78, Ensembl Release: 56.
Description: Fatty aldehyde dehydrogenase
Structure Features
Structure Features Explanation of Structure Features Field PS00687: Aldehyde dehydrogenases glutamic acid active site
PFAM predictions Explanation of PFAM predictions
Accession Domain Start Stop E-value Release No.
PF00171 Aldedh, Aldehyde dehydrogenase family. 26 446 5e-82 23.0
 
Operons/Regulons
Type operon
Genes
GeneProduct
PA0364 probable oxidoreductase
PA0365 hypothetical protein
PA0366 probable aldehyde dehydrogenase
Evidence Computationally Predicted
PubMed 18988623
Cross-Reference DOOR-13176
Microarray Expression Data
NCBI GEO Link
Sequence data
Upstream 500 BP Region GGCGCAGGAAGCTCTCGACGTGGCTTTCGTACTCGGCGAACAGCTCGGCGATGATCGCCTGCTTGTTCGGGTAGTGGTAGTAGAGGTTCCCAGGCGATAT ACCCAGGTGGGTGGCGATATGGTTGGTGGTGACGCTGCGCTCGCCCTGGGCGTTGAACAGTTCCAGGCTGGCCTGGGCGATGCGATCGCGGGTCTTGATG CGTGGTGCCATGGGGACGACGGGCTCGTTCGGGTAACAGTGCGGGGCGCGCCCCGCCGTGACAGCGTAGAAGGTACACAAAGCCGGCCGCCCGGGTCAGC CCCCGGGGGTGGCGGCCGGCGACCGGCCCGCCTTTCGTTGGGTACGCAAGCGCCGGGCTGGCAGGCATGCTGTTTGACACTTTAGAGTATTTACTCTAGA AATCCAGCGACGCAGCGAAATTCATCGGACCGAACCAGGTCCGCCATAACGACAGACGCGCGGCCACGCAGCCGCCCACGCTTCGCCGAGGAGCCAGCCC

BLAST search against this genome or other genomes in database
Need more than 500 BP? Try our sequence retrieval tool or view intergenic regions in GBrowse.

DNA Sequence ATGGTCGCCGATATCGCCTACCTGCAGCAGAGCCAGCAGGAAATCAACCAGCTCGAAGCCCTCTTCGCCCGCCAGCGCGCCGCCTACCTGGCGCAGCCGA TGCCCGACGCCACGCAGCGCGTGCAGTGGCTGAAGGCCCTGCGCGACCTGCTGTTCAAGGAACAGCAGGCACTGATCGAGGCCATCGACCGGGACTTCAG CGCGCGCTCCGCCGACGAGACCCTGCTCGCCGAGATCATGCCCAGCCTGCACGGCATCCACTACGCCGCCAAGCGCGTGAAGAAATGGATGAAGCCCGCG CGCCGCGCGGTCGGCCTGCAATTCCAGCCGGCCTCGGCCCAGGTGGTGTACCAGCCGCTGGGCGTGGTCGGGGTGATCGTGCCTTGGAACTATCCGCTGT TCCTCTCCATCGGCCCGCTGACCGGGGCCCTCGCCGCCGGCAACCGGGTGATGATCAAGATGAGCGAGTCGACCCCGGCCACCGGGCGCCTGCTCAAGGA CCTGCTGGCGCGGATCTTCCCCGAGGACCAGGTCGCCGTGGTGCTAGGCGAGGTAGACGTCGGCGTGGCCTTTTCCAAGCTGCCGTTCGACCACCTGCTG TTCACCGGCGCCACCAGCGTCGGCAAGCACGTGATGCGCGCCGCCGCCGAGAACCTGACCCCGGTCACCCTGGAGCTGGGCGGCAAGTCGCCGGCGATCG TCTCCGACAGCGTGCCGATGAAGGACGCCGCCGAGCGGATCGCCTTCGGCAAGAGCCTCAACGCCGGGCAGACCTGCGTCGCGCCCGACTACGTGCTGGT ACCGAGCCGGCGCGTCGAGGAATTCGTCAGTCAGTACAAGGAGGTGGTCCAGGGCTTCTTCCCGCGTCTTTCGGACAACCCCGACTACACCGCGATCATC AACGAGCGCCAGCTCGGCCGCCTCCGGGGCTATCTCGACGACGCCCGCGAGAAGGGCGCGACCCTCGTCCCGCTGTTCGCCGAAGGCCAGCAACGGCGCC TGCCGCAGACGCTGCTTCTGAACGTCAGCGACGACATGAAAGTGATGCAGGAGGAAATCTTCGGCCCGCTGCTGCCGGTGATCCCCTACGAGCGCCTGGA AGACGCCCTGGCCTACGTCAACCAGCGCCCGCGACCGCTGGCCCTGTACTACTTCGGCTACGACAAGGCGCAGCAGCAGCGCGTGCTGCACGAGACCCAC TCAGGCGGTGTGTGTCTGAACGACACCCTGCTGCATGTCGCCCAGGACGACATCCCGTTCGGTGGCGTCGGTCCCTCCGGCATGGGCCACTACCATGGCC ACGAAGGCTTCCTCACCTTCAGCAAGGCCAAGGGCGTGTTCAGCAAGCCGCGCTTCAACGCCGCGCGAATGATCTACCCCCCCTACGGCAAGTCGATCCA GAAGCTCGTCTACAAGCTGTTCGTGCGCTGA

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Downstream 500 BP region Click here to view the nucleotide sequence of the region 500 BP downstream of this gene.

Protein Sequence MVADIAYLQQSQQEINQLEALFARQRAAYLAQPMPDATQRVQWLKALRDLLFKEQQALIEAIDRDFSARSADETLLAEIMPSLHGIHYAAKRVKKWMKPA RRAVGLQFQPASAQVVYQPLGVVGVIVPWNYPLFLSIGPLTGALAAGNRVMIKMSESTPATGRLLKDLLARIFPEDQVAVVLGEVDVGVAFSKLPFDHLL FTGATSVGKHVMRAAAENLTPVTLELGGKSPAIVSDSVPMKDAAERIAFGKSLNAGQTCVAPDYVLVPSRRVEEFVSQYKEVVQGFFPRLSDNPDYTAII NERQLGRLRGYLDDAREKGATLVPLFAEGQQRRLPQTLLLNVSDDMKVMQEEIFGPLLPVIPYERLEDALAYVNQRPRPLALYYFGYDKAQQQRVLHETH SGGVCLNDTLLHVAQDDIPFGGVGPSGMGHYHGHEGFLTFSKAKGVFSKPRFNAARMIYPPYGKSIQKLVYKLFVR

BLAST search against this genome or other genomes in database
View precomputed BLAST results against all genomes at NCBI BLINK
References
PubMed Purification and characterization of the coniferyl aldehyde dehydrogenase from Pseudomonas sp. Strain HR199 and molecular characterization of the gene.
Achterholt S, Priefert H, Steinbuchel A.
J Bacteriol. 1998 Sep;180(17):4387-91.
PMID: 9721273
 
Alternate Annotations and Cross-References
TIGR NTL03PA00367
Systomonas PA0366
RefSeq NP_249057.1
GI 15595563
KEGG PA0366
GBrowse Click here for a GBrowse View of this and other annotations.
PseudoCyc Click here to view metabolic pathways in PseudoCyc.


We thank Cystic Fibrosis Foundation Therapeutics, Inc. for critical funding support for the Pseudomonas Genome Database. When acknowledging use of the database, please cite the article by Winsor et al. (2009; PMID:18978025) and not the web site URL. Thank you!

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