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               PA0380               
Key to diagram


View in GBrowse: 16 putative orthologs View metabolic pathways using PseudoCyc Acknowledgements for this annotation
Gene Information
Strain Pseudomonas aeruginosa PAO1 (Tax ID: 208964) Replicon Chromosome(5651 genes, 6264404 bp) [ RefSeq ]
Gene name   Alternate Gene Names
Locus tag PA0380 (View 5 updates) Submit an Update GenBank Identifier (GI) 15595577 (Precomputed BLAST results at BLINK )
Genomic location 423460 - 423660 (+) Feature type CDS 
Transposon Mutant Available?Transposon mutant library help Yes (View in GBrowse) Pseudomonas Ortholog Group Explanation of Orthologous Groups
Product Information
Product Name conserved hypothetical protein (Class 4  Explanation of Product Name Confidence)
Alternate Product Names
Subcellular localization
Unknown (Class 3Explanation of Localization Confidence)
Alternate Annotations and Cross-References
TIGR NTL03PA00381
Systomonas PA0380
RefSeq NP_249071.1
GI 15595577
KEGG PA0380
GBrowse Click here for a GBrowse View of this and other annotations.
PseudoCyc Click here to view metabolic pathways in PseudoCyc.
Function Classification / Gene Ontology (GO)
PseudoCAP Function Class Hypothetical, unclassified, unknown
GO Accession GO Term Evidence
Molecular Function
GO:0003824 catalytic activity IEA
Biological Process
GO:0009228 thiamin biosynthetic process IEA
Cellular Component
COG PredictionExplanation of COG predictions
Accession Description Category
COG2104 ThiS, Sulfur transfer protein involved in thiamine biosynthesis [Coenzyme metabolism]. Coenzyme metabolism
Homology
BLINK Precomputed BLAST results at BLINK
Homologs Explanation of Homologs Field 60% similar to hypothetical protein [Porphyra purpurea]
Structure Features
PFAM predictions Explanation of PFAM predictions
Accession Domain Start Stop E-value Release No.
PF02597 ThiS, ThiS family. 3 66 3e-12 23.0
 
Microarray Expression Data
NCBI GEO Link
Upstream 500 BP Region CTATCACCGGAGTCTTGTCCATGCTTCGTCCCTTCCTGTTGTTGGCGGCATTTTTCGGTTTCACCGGCGTGGCCCTCGGGGCGTTCGCCGCCCACGGCCT GAAGAAGCAGCTGAGCGCCGAGTACCTGGCGGTATTCCAGACCGGCGTGCACTACCAGTTGATCCATGCCCTGGCGCTGTTCGGCGTGGCGCTGCTCGCC ACCCGCCTGGACGGCCGCCTGGTGAGCGCGGCGGGTGGCCTGTTCACGCTGGGCATCCTGCTGTTCTCCGGCAGCCTCTACCTGCTGACCCTAAGTGGCA TCGGCAAGCTCGGCATCGTCACCCCGTTCGGCGGCGTCTCCTTCCTCGCCGGCTGGCTGTGCCTGGGGCTGGCCGCCTGGCGCCTGGGCAACGCCTGAGA CCGGTTGCCTCAGGCGGCGCACTTGTCGACAAGGCGCCTTGGTCATCGGGGTGGATCGGGCTAGAATGCCGCTCCCTTTCACTTTCGTGACCGTCCAGCC

BLAST search against this genome or other genomes in database
Need more than 500 BP? Try our sequence retrieval tool or view intergenic regions in GBrowse.

DNA Sequence ATGCAGATTCAACTGAACGGCGAGCCCTTCGAGCTGCCCGACGCGCAGAGCGTCGCGGACCTGCTGGCCCGCTTGGAGCTTGGCGGCCGCCGCGTGGCCG TCGAGCTGAACCTGGATATCGTGCCGCGCAGCCAGCACGCCAGCACCGCGCTCAAGGATGGCGACCGCGTGGAGATCGTCCACGCCATCGGCGGCGGCTA G

BLAST search against this genome or other genomes in database

Downstream 500 BP region Click here to view the nucleotide sequence of the region 500 BP downstream of this gene.
Protein Sequence MQIQLNGEPFELPDAQSVADLLARLELGGRRVAVELNLDIVPRSQHASTALKDGDRVEIVHAIGGG

BLAST search against this genome or other genomes in database
View precomputed BLAST results against all genomes at NCBI BLINK
SNPs NOTE: This feature is currently open to beta-testing. We welcome feedback on how to improve this new resource. Please send any comments to pseudocap-mail@sfu.ca.

Showing SNPs occurring in PA0380 gene of Pseudomonas aeruginosa PAO1, Chromosome (423460 to 423660 bp)


Displaying the first five SNPs out of a total of 7 found in all isolate strains ( View all 7 )
Strain Type Mutation Description Effect Details GBrowse
DNA Protein
Pseudomonas aeruginosa PA7 Transversion g.423484C>G p.Pro9Ala
 Missense
CCC(Pro) -> GCC(Ala) 		SNP-483869 View
Pseudomonas aeruginosa PA7 Transversion g.423495G>C
Silent
CTG(Leu) -> CTC(Leu) 		SNP-483870 View
Pseudomonas aeruginosa C3719 Transition g.423532T>C
Silent
TTG(Leu) -> CTG(Leu) 		SNP-12658 View
Pseudomonas aeruginosa PACS2 Transition g.423532T>C
Silent
TTG(Leu) -> CTG(Leu) 		SNP-104572 View
Pseudomonas aeruginosa PA14 Transition g.423532T>C
Silent
TTG(Leu) -> CTG(Leu) 		SNP-184422 View
Select to view SNPs in a specific strain
SNP Map
Operons/Regulons
Type operon
Genes
GeneProduct
PA0380 conserved hypothetical protein
thiG thiamine biosynthesis protein, thiazole moiety
Evidence Computationally Predicted
PubMed 18988623
Cross-Reference DOOR-13180
PubMed  


We thank Cystic Fibrosis Foundation Therapeutics, Inc. for critical funding support for the Pseudomonas Genome Database. When acknowledging use of the database, please cite the article by Winsor et al. (2009; PMID:18978025) and not the web site URL. Thank you!

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