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               PA0394               
Key to diagram


View in GBrowse: 16 putative orthologs View metabolic pathways using PseudoCyc Acknowledgements for this annotation
Gene Information
Strain Pseudomonas aeruginosa PAO1 (Tax ID: 208964) Replicon Chromosome(5651 genes, 6264404 bp) [ RefSeq ]
Gene name   Alternate Gene Names yggS
Locus tag PA0394 (View 6 updates) Submit an Update GenBank Identifier (GI) 15595591 (Precomputed BLAST results at BLINK )
Genomic location 436355 - 435663 (-) Feature type CDS 
Transposon Mutant Available?Transposon mutant library help Yes (View in GBrowse) Pseudomonas Ortholog Group Explanation of Orthologous Groups
Product Information
Product Name conserved hypothetical protein (Class 4  Explanation of Product Name Confidence)
Alternate Product Names
Subcellular localization
Cytoplasmic (Class 1Explanation of Localization Confidence)
Cytoplasmic (Class 3Explanation of Localization Confidence)
Alternate Annotations and Cross-References
TIGR NTL03PA00395
Systomonas PA0394
RefSeq NP_249085.1
GI 15595591
KEGG PA0394
GBrowse Click here for a GBrowse View of this and other annotations.
PseudoCyc Click here to view metabolic pathways in PseudoCyc.
Function Classification / Gene Ontology (GO)
PseudoCAP Function Class Hypothetical, unclassified, unknown
Homology
BLINK Precomputed BLAST results at BLINK
Homologs Explanation of Homologs Field 68% similar to hypothetical protein YggS [Escherichia coli]
100% identical to HYPOTHETICAL 24.5 KD PROTEIN IN PILT 5'REGION (ORF5) [Pseudomonas aeruginosa]
Most Similar Human Homolog
ENSP00000333551, Percent Identity: 38.60%, E-Value: 3e-23, Ensembl Release: 56.
Description: Proline synthetase co-transcribed bacterial homolog protein
Structure Features
Structure Features Explanation of Structure Features Field PF01168/PS01211: Uncharacterized protein family UPF0001 signature
PFAM predictions Explanation of PFAM predictions
Accession Domain Start Stop E-value Release No.
PF01168 Ala_racemase_N, Alanine racemase, N-terminal domain. 7 224 8e-43 23.0
 
Microarray Expression Data
NCBI GEO Link
Upstream 500 BP Region ATACCGCGCCGGCGCCACGGTTCTGGTTGAAGGCGTTGACCCGGAAACGCGCGACGCCCGGCACCTCGAAGGAGAAGTCGGTCTCGAGGAATTCCTCGAA GTCCTTGCGCTGCTTGTCGTTCATGATGTCGTAGATCAGCGCATGCACCTGCTTGTGTTCCAGCGGTGGCAGGTTGATCCGGCGTACATCGCCATCCACC CGGATCATGGGTGGCAGGCCGGCGGAGAGGTGCAGGTCCGAAGCGCCCTGTTTGGCACTGAAGGCGAGCAGCTCGGTAATATCCATGGGACTCCCCAATT ACAAGCAAGCAGGTAGAATGCCGCCAAAGCCGCCGTCTCGGACAAGGAAAACACCGGATGAGCCAGGGTGCTTCCAGGACACGCGTGGTGTCCTGCGCCA GACGCGGAACCTCGACACTGGAACAGGAAGATGGCCATCGAGGCCGGCGGTTTCGAGGGCGTCGAGCCGACGCCGACCGCACTTCCATAGGGCGCAGGTA

BLAST search against this genome or other genomes in database
Need more than 500 BP? Try our sequence retrieval tool or view intergenic regions in GBrowse.

DNA Sequence ATGTCCACGATAGCAGAGAATATTGCAAAGGTTGCCGCGCGCATCCGTGAGGCAGCGCAAGCTGCGGGGCGCGATCCGGCCACGGTCGGCCTGCTCGCCG TGAGCAAGACCAAGCCCGCCGCCGCGGTGCGCGAGGCGCACGCCGCCGGCCTTCGCGACTTCGGCGAAAACTACCTGCAGGAGGCCCTCGGCAAGCAGGC CGAACTGGCCGACCTGCCCTTGAACTGGCACTTCATCGGCCCCATCCAGTCGAACAAGACGCGGCCCATCGCCGAGCATTTCCAGTGGGTGCACTCGGTG GACCGGTTGAAGATCGCGCAGCGCCTGTCGGAGCAACGCCCGGCCGGGCTGCCGCCCCTGAATGTCTGCCTGCAGGTCAACGTCAGCGGCGAAGCCAGCA AGTCCGGCTGCGCCCCCGAGGACCTGCCGGCCCTGGCCGAGGCCGTGAAGCAACTGCCCAACCTCCGATTGCGTGGCCTGATGGCCATCCCCGAACCCAC CGCCGAACGCGCCGCGCAACACGCCGCGTTCGCCCGCCTGCGCGAACTGCTGCTGGACCTGAACCTTGGCCTGGACACCCTGTCCATGGGCATGAGCGAC GACCTCGAGGCAGCCATCGGCGAAGGTGCGACCTGGGTCCGCATCGGTACCGCCCTGTTCGGCGCCCGCGACTACGGCGCGCCGGCTTCTTGA

BLAST search against this genome or other genomes in database

Downstream 500 BP region Click here to view the nucleotide sequence of the region 500 BP downstream of this gene.
Protein Sequence MSTIAENIAKVAARIREAAQAAGRDPATVGLLAVSKTKPAAAVREAHAAGLRDFGENYLQEALGKQAELADLPLNWHFIGPIQSNKTRPIAEHFQWVHSV DRLKIAQRLSEQRPAGLPPLNVCLQVNVSGEASKSGCAPEDLPALAEAVKQLPNLRLRGLMAIPEPTAERAAQHAAFARLRELLLDLNLGLDTLSMGMSD DLEAAIGEGATWVRIGTALFGARDYGAPAS

BLAST search against this genome or other genomes in database
View precomputed BLAST results against all genomes at NCBI BLINK
SNPs NOTE: This feature is currently open to beta-testing. We welcome feedback on how to improve this new resource. Please send any comments to pseudocap-mail@sfu.ca.

Showing SNPs occurring in PA0394 gene of Pseudomonas aeruginosa PAO1, Chromosome (435663 to 436355 bp)


Displaying the first five SNPs out of a total of 30 found in all isolate strains ( View all 30 )
Strain Type Mutation Description Effect Details GBrowse
DNA Protein
Pseudomonas aeruginosa PA7 Transition g.435671C>T p.Ala229Thr
 Missense
GCT(Ala) -> ACT(Thr) 		SNP-484092 View
Pseudomonas aeruginosa PA7 Transversion g.435690G>C
Silent
GCC(Ala) -> GCG(Ala) 		SNP-484093 View
Pseudomonas aeruginosa PA7 Transition g.435729A>G
Silent
GGT(Gly) -> GGC(Gly) 		SNP-484094 View
Pseudomonas aeruginosa PA7 Transversion g.435736C>G p.Gly207Ala
 Missense
GGC(Gly) -> GCC(Ala) 		SNP-484095 View
Pseudomonas aeruginosa PA7 Transition g.435744T>C
Silent
GCA(Ala) -> GCG(Ala) 		SNP-484096 View
Select to view SNPs in a specific strain
SNP Map
Operons/Regulons
Type operon
Genes
GeneProduct
PA0392 conserved hypothetical protein
proC pyrroline-5-carboxylate reductase
PA0394 conserved hypothetical protein
Evidence Computationally Predicted
PubMed 18988623
Cross-Reference DOOR-13184
Genomic Context
Genomic context Explanation of Genomic Context Field - Upstream of pilT
PubMed Characterisation of a Pseudomonas aeruginosa twitching motility gene and evidence for a specialised protein export system widespread in eubacteria.
Whitchurch CB, Hobbs M, Livingston SP, Krishnapillai V, Mattick JS.
Gene. 1991 May 15;101(1):33-44.
PMID: 1676385
PSORTb 3.0: Improved protein subcellular localization prediction with refined localization subcategories and predictive capabilities for all prokaryotes.
Yu NY, Wagner JR, Laird MR, Melli G, Rey S, Lo R, Dao P, Sahinalp SC, Ester M, Foster LJ, Brinkman FS.
Bioinformatics. 2010 May 13; [Epub ahead of print]
PMID: 20472543
 


We thank Cystic Fibrosis Foundation Therapeutics, Inc. for critical funding support for the Pseudomonas Genome Database. When acknowledging use of the database, please cite the article by Winsor et al. (2009; PMID:18978025) and not the web site URL. Thank you!

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