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               PA0964               
Key to diagram


View in GBrowse: 16 putative orthologs View metabolic pathways using PseudoCyc Acknowledgements for this annotation
Gene Information
Strain Pseudomonas aeruginosa PAO1 (Tax ID: 208964) Replicon Chromosome(5651 genes, 6264404 bp) [ RefSeq ]
Gene name pmpR  Alternate Gene Names yebC
Locus tag PA0964 (View 5 updates) Submit an Update GenBank Identifier (GI) 15596161 (Precomputed BLAST results at BLINK )
Genomic location 1050301 - 1051047 (+) Feature type CDS 
Transposon Mutant Available?Transposon mutant library help Yes (View in GBrowse) Pseudomonas Ortholog Group Explanation of Orthologous Groups
Product Information
Product Name pqsR-mediated PQS regulator, PmpR (Class 4  Explanation of Product Name Confidence)
Alternate Product Names
Subcellular localization
Cytoplasmic (Class 3Explanation of Localization Confidence)
Alternate Annotations and Cross-References
TIGR NTL03PA00965
Systomonas PA0964
RefSeq NP_249655.1
GI 15596161
KEGG PA0964
GBrowse Click here for a GBrowse View of this and other annotations.
PseudoCyc Click here to view metabolic pathways in PseudoCyc.
Function Classification / Gene Ontology (GO)
PseudoCAP Function Class Hypothetical, unclassified, unknown
Homology
BLINK Precomputed BLAST results at BLINK
Homologs Explanation of Homologs Field 78% similar to hypothetical protein YebC [Escherichia coli]
Most Similar Human Homolog
ENSP00000258975, Percent Identity: 25.10%, E-Value: 1e-15, Ensembl Release: 56.
Description: Coiled-coil domain-containing protein 44
Structure Features
Structure Features Explanation of Structure Features Field PF01709: Domain of unknown function DUF28
PFAM predictions Explanation of PFAM predictions
Accession Domain Start Stop E-value Release No.
PF01709 DUF28, Domain of unknown function DUF28. 5 238 1e-108 23.0
 
Microarray Expression Data
NCBI GEO Link
Upstream 500 BP Region CGCTGCACCACCCGTTCACCTCGCCCAAGTGCACCCCGGCTGAGCTTGAGGCCAATCCGGGCGCGGCACTTTCCCGCGCCTACGACATGGTGCTCAACGG TACCGAGCTGGGTGGCGGTTCCATCCGTATCCATGACAAGTCCATGCAGCAGGCGGTGTTCCGTGTGCTGGGCATCGACGAGGCGGAACAGGAAGAGAAA TTCGGCTTCCTGCTCGACGCGCTCAAGTACGGTGCGCCGCCGCATGGCGGCCTGGCCTTCGGCCTGGATCGCCTGGTCATGCTGATGACCGGTGCATCGT CTATCCGCGAAGTGATCGCCTTCCCGAAGACCCAGAGCGCTGGCGACGTCATGACCCAGGCACCGGGTTCCGTGGACGGCAAGGCCCTGCGCGAGCTGCA CATTCGCCTGCGCGAGCAGCCGAAGGCCGAGTGATTCGAATCAACCCGCGGAGGCGCCGCTTGCGGCGCCTCCTGCCGAGAGAGCAATACGGAGTGAGTT

BLAST search against this genome or other genomes in database
Need more than 500 BP? Try our sequence retrieval tool or view intergenic regions in GBrowse.

DNA Sequence ATGGCTGGTCATTCTAAATGGGCCAACATCAAGCACCGCAAAGAGCGGCAAGATGCCAAGAAAGGCAAGATCTTTACCAAGCTGATCCGTGAGCTGACCG TCGCTGCAAGGCAGGGCGGCGGCGTCCCGGCGGACAACCCGCGTCTGCGCCTGGCCGTGGACAAGGCGCTGACCGCCAACATGACCCGCGATACCATCGA TCGTGCCATTGCGCGCGGCGTCGGCTCCAACGATGCCGACAACATGGTCGAGCTTTCCTATGAAGGTTATGCGCCGAGCGGCGTAGCGATCATCGTCGAG GCGATGACCGACAACCGCAACCGTACCGCTGCCGAAGTGCGTCATGCCTTCAGCAAGTGTGGCGGCAACCTGGGCACCGATGGTTCGGTCGCCTACATGT TCGAGCGCAAGGGACAGATCAGCTTCGCTCCCGGCGTGGACGAGGAAGCGCTGATGGACGCGGCCCTGGAGGCTGGCGCCGATGACGTGGTAGTCAACGA CGATGGCTCCATCGACGTGTTCACCACCTTCGCCGACTTCATTTCGGTGAACGAGGCGCTGGCCGCCGCCGGATTCAAGGGCGACGAAGCCGAAGTCACC ATGATCCCTTCGACCACCGCGACCCTGGACCTGGAAACCGCGCAGAAGGTGCTCAAGCTGATCGACATGCTCGAGGACCTGGACGACGTGCAGAACGTCT ATTCCAATGCCGATATCCCGGACGACGTGATGGCGCAGCTCGGCTGA

BLAST search against this genome or other genomes in database

Downstream 500 BP region Click here to view the nucleotide sequence of the region 500 BP downstream of this gene.
Protein Sequence MAGHSKWANIKHRKERQDAKKGKIFTKLIRELTVAARQGGGVPADNPRLRLAVDKALTANMTRDTIDRAIARGVGSNDADNMVELSYEGYAPSGVAIIVE AMTDNRNRTAAEVRHAFSKCGGNLGTDGSVAYMFERKGQISFAPGVDEEALMDAALEAGADDVVVNDDGSIDVFTTFADFISVNEALAAAGFKGDEAEVT MIPSTTATLDLETAQKVLKLIDMLEDLDDVQNVYSNADIPDDVMAQLG

BLAST search against this genome or other genomes in database
View precomputed BLAST results against all genomes at NCBI BLINK
SNPs NOTE: This feature is currently open to beta-testing. We welcome feedback on how to improve this new resource. Please send any comments to pseudocap-mail@sfu.ca.

Showing SNPs occurring in PA0964 gene of Pseudomonas aeruginosa PAO1, Chromosome (1050301 to 1051047 bp)


Displaying the first five SNPs out of a total of 50 found in all isolate strains ( View all 50 )
Strain Type Mutation Description Effect Details GBrowse
DNA Protein
Pseudomonas aeruginosa PA14 Transition g.1050375T>C
Silent
TTT(Phe) -> TTC(Phe) 		SNP-182243 View
Pseudomonas aeruginosa PA7 Transition g.1050375T>C
Silent
TTT(Phe) -> TTC(Phe) 		SNP-309281 View
Pseudomonas aeruginosa PA7 Transition g.1050408A>G
Silent
GCA(Ala) -> GCG(Ala) 		SNP-309282 View
Pseudomonas aeruginosa PA7 Transition g.1050410G>A p.Arg37Lys
 Missense
AGG(Arg) -> AAG(Lys) 		SNP-309283 View
Pseudomonas aeruginosa PA7 Transition g.1050426C>T
Silent
GTC(Val) -> GTT(Val) 		SNP-309284 View
Select to view SNPs in a specific strain
SNP Map
Operons/Regulons
Type operon
Genes
GeneProduct
aspS aspartyl-tRNA synthetase
pmpR pqsR-mediated PQS regulator, PmpR
Evidence Computationally Predicted
PubMed 18988623
Cross-Reference DOOR-13311
PubMed The YebC family protein PA0964 negatively regulates the Pseudomonas aeruginosa quinolone signal system and pyocyanin production.
Liang H, Li L, Dong Z, Surette MG, Duan K.
J Bacteriol. 2008 Sep;190(18):6217-27. Epub 2008 Jul 18.
PMID: 18641136
 


We thank Cystic Fibrosis Foundation Therapeutics, Inc. for critical funding support for the Pseudomonas Genome Database. When acknowledging use of the database, please cite the article by Winsor et al. (2009; PMID:18978025) and not the web site URL. Thank you!

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