contact us| site map | view my clipboard
Add this annotation to your clipboard
               PA1987               
Key to diagram


View in GBrowse: (?) 16 putative orthologs View metabolic pathways using PseudoCyc Acknowledgements for this annotation
Gene Information
Strain Pseudomonas aeruginosa PAO1 (Tax ID: 208964) Replicon Chromosome(5651 genes, 6264404 bp) [ RefSeq ]
Gene name pqqC  Alternate Gene Names
Locus tag PA1987 (View 8 updates) GenBank Identifier (GI) 15597183 (Precomputed BLAST results at BLINK )
Genomic location 2172913 - 2173665 (+) Feature type CDS 
Transposon Mutant Available?Transposon mutant library help No transposon mutant available yet Pseudomonas Ortholog Group Explanation of Orthologous Groups
Product Information
Product Name pyrroloquinoline quinone biosynthesis protein C (Class 2  Explanation of Product Name Confidence)
Alternate Product Names coenzyme PQQ synthesis protein C
Subcellular localization
Cytoplasmic (Class 3Explanation of Localization Confidence)
Function Classification / Gene Ontology (GO)
PseudoCAP Function Class Biosynthesis of cofactors, prosthetic groups and carriers
GO Accession GO Term Evidence
Molecular Function
Biological Process
GO:0051188 cofactor biosynthetic process ISS
GO:0018189 pyrroloquinoline quinone biosynthetic process IEA
Cellular Component
COG PredictionExplanation of COG predictions
Accession Description Category
COG5424 COG5424, Pyrroloquinoline quinone (Coenzyme PQQ) biosynthesis protein C [Coenzyme metabolism]. Coenzyme metabolism
TIGRFAM predictionExplanation of TIGRFAM predictions
Accession Name Function Significance Role Sub Role Release No.
TIGR02111 PQQ_syn_pqqC coenzyme PQQ biosynthesis protein C 3.5e-176 Biosynthesis of cofactors, prosthetic groups, and carriers Other 8.0
Pathways
Pathways Explanation of Pathways Field
Name Database Xref
Pyrroloquinoline quinone biosynthesis PseudoCAP
Homology
BLINK Precomputed BLAST results at BLINK
Homologs Explanation of Homologs Field 84% similar to pqqC gene product of [Klebsiella pneumoniae]
Structure Features
PFAM predictions Explanation of PFAM predictions
Accession Domain Start Stop E-value Release No.
PF03070 TENA_THI-4, TENA/THI-4/PQQC family. 12 223 1e-55 23.0
 
Genomic Context
Genomic context Explanation of Genomic Context Field - Third of five ORF cluster
- pqqF is elsewhere.
Operons/Regulons
Type operon
Genes
GeneProduct
pqqA pyrroloquinoline quinone biosynthesis protein A
pqqB pyrroloquinoline quinone biosynthesis protein B
pqqC pyrroloquinoline quinone biosynthesis protein C
pqqD pyrroloquinoline quinone biosynthesis protein D
pqqE pyrroloquinoline quinone biosynthesis protein E
PA1990 probable peptidase
Evidence Computationally Predicted
PubMed 18988623
Cross-Reference DOOR-13522
Microarray Expression Data
NCBI GEO Link
Sequence data
Upstream 500 BP Region TCGATGGCGAGCCTTTCGCCATTCCGGCCTGTCCGCGCCTGCGCTTCACCGCGATCCCCCTGCGCAGTAGCGCGCCGCCGTATTCCCCGCATCGCGGCGA TCCGCATCCGGGCGACAACATCGGCCTGTTCGTCGAGGACCTCGATAGCGCCGGTGCGCTGTTCTATGCACCGGGCCTCGGCGAGGTGGACGAGGCGCTG CTCGAATGGATGCGCCGCGCCGACTGCCTGCTGGTGGACGGTACGCTCTGGCGCGACGACGAGATGCTGGTCTGCGAGGTCGGCGACAAGCTCGGCCGGC AGATGGGGCACCTGGCGCAGAGCGGGCCGGGCGGCATGCTCGAGGTGCTGGCGAAGGTGCCGGCCGCGCGCAAGGTGCTCATCCACATCAACAACACCAA TCCCATCCTCGACACCGCTTCGGCCGAACGCGCCGAGCTGGATGCCAGTGGCATCGAAGTGGCCTGGGATGGCATGCACATCCAGCTGTAGGGGGCCAAC

BLAST search against this genome or other genomes in database
Need more than 500 BP? Try our sequence retrieval tool or view intergenic regions in GBrowse.

DNA Sequence ATGAGCCGTGCCGCCATGGATCGCGCCGAATTCGAACGGGCGCTGCGCGACAAGGGACGCTACTACCATATCCACCATCCGTTCCATGTCGCGATGTACG AGGGCCGTGCCAGTCGCGAACAGATCCAGGGCTGGGTGGCGAACCGTTTCTACTACCAGGTCAACATCCCGCTGAAGGACGCGGCGATCCTGGCCAACTG TCCCGACCGCGAGGTCCGCCGCGAGTGGATCCAGCGTATCCTCGACCACGACGGCGCCCCCGGCGAGGCGGGCGGCATCGAGGCCTGGCTGCGTCTGGCG GAAGCGGTGGGCCTGGAGCGCGAGCAGGTGCTGTCCGAGGAGCGGGTGCTGCCCGGCGTGCGCTTCGCCGTCGACGCCTACGTCAACTTCGCCCGTCGCG CCAGTTGGCAGGAGGCGGCGAGCAGTTCGCTGACCGAACTCTTCGCCCCGCAGATCCACCAGTCGCGGCTGGACAGCTGGCCGCGCCACTATCCGTGGAT CGAGGCGGCCGGCTACGAGTATTTCCGCAGTCGCCTGGCCCAGGCCCGGCGCGACGTCGAGCACGGCCTGCGGATCACCCTGGAGCACTATCGGACCCGC GAGGCACAGGAACGCATGCTGGATATCCTGCAATTCAAGCTGGACGTGTTGTGGAGCATGCTCGACGCGATGAGCATGGCCTACGAACTCGAACGCCCGC CGTACCACACGGTGACCCGCGAGCGGGTCTGGCATCGGGGGCTGGCATCATGA

BLAST search against this genome or other genomes in database


Downstream 500 BP region Click here to view the nucleotide sequence of the region 500 BP downstream of this gene.

Protein Sequence MSRAAMDRAEFERALRDKGRYYHIHHPFHVAMYEGRASREQIQGWVANRFYYQVNIPLKDAAILANCPDREVRREWIQRILDHDGAPGEAGGIEAWLRLA EAVGLEREQVLSEERVLPGVRFAVDAYVNFARRASWQEAASSSLTELFAPQIHQSRLDSWPRHYPWIEAAGYEYFRSRLAQARRDVEHGLRITLEHYRTR EAQERMLDILQFKLDVLWSMLDAMSMAYELERPPYHTVTRERVWHRGLAS

BLAST search against this genome or other genomes in database
View precomputed BLAST results against all genomes at NCBI BLINK
References
PubMed Acinetobacter calcoaceticus genes involved in biosynthesis of the coenzyme pyrrolo-quinoline-quinone: nucleotide sequence and expression in Escherichia coli K-12.
Goosen N, Horsman HP, Huinen RG, van de Putte P.
J Bacteriol. 1989 Jan;171(1):447-55.
PMID: 2536663
Nucleotide sequence and structure of the Klebsiella pneumoniae pqq operon.
Meulenberg JJ, Sellink E, Riegman NH, Postma PW.
Mol Gen Genet. 1992 Mar;232(2):284-94.
PMID: 1313537
Synthesis of pyrroloquinoline quinone in vivo and in vitro and detection of an intermediate in the biosynthetic pathway.
Velterop JS, Sellink E, Meulenberg JJ, David S, Bulder I, Postma PW.
J Bacteriol. 1995 Sep;177(17):5088-98.
PMID: 7665488
 
Alternate Annotations and Cross-References
TIGR NTL03PA01987
Systomonas PA1987
RefSeq NP_250677.1
GI 15597183
KEGG PA1987
GBrowse Click here for a GBrowse View of this and other annotations.
PseudoCyc Click here to view metabolic pathways in PseudoCyc.


We thank Cystic Fibrosis Foundation Therapeutics, Inc. for critical funding support for the Pseudomonas Genome Database. When acknowledging use of the database, please cite the article by Winsor et al. (2009; PMID:18978025) and not the web site URL. Thank you!

| What's New | FAQs | Cystic Fibrosis | Pseudomonas aeruginosa | Who is Involved? | Annotation Approach | Get Involved | Supplemental Data | Links to More Analyses | Site Map | Acknowledgements | Contact Us |