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               PA2357               
Key to diagram


View in GBrowse: (?) 9 putative orthologs View metabolic pathways using PseudoCyc Acknowledgements for this annotation
Gene Information
Strain Pseudomonas aeruginosa PAO1 (Tax ID: 208964) Replicon Chromosome(5651 genes, 6264404 bp) [ RefSeq ]
Gene name msuE  Alternate Gene Names
Locus tag PA2357 (View 4 updates) GenBank Identifier (GI) 15597553 (Precomputed BLAST results at BLINK )
Genomic location 2605275 - 2604715 (-) Feature type CDS 
Transposon Mutant Available?Transposon mutant library help No transposon mutant available yet Pseudomonas Ortholog Group Explanation of Orthologous Groups
Product Information
Product Name NADH-dependent FMN reductase MsuE (Class 1  Explanation of Product Name Confidence)
Alternate Product Names
Subcellular localization
Unknown (Class 3Explanation of Localization Confidence)
Function Classification / Gene Ontology (GO)
PseudoCAP Function Class Carbon compound catabolism
Central intermediary metabolism
GO Accession GO Term Evidence
Molecular Function
Biological Process
GO:0044248 cellular catabolic process IDA
GO:0015978 carbon utilization by utilization of organic compounds IDA
GO:0008152 metabolic process IDA
GO:0006790 sulfur metabolic process IDA
Cellular Component
COG PredictionExplanation of COG predictions
Accession Description Category
COG0431 COG0431, Predicted flavoprotein [General function prediction only]. General function prediction only
TIGRFAM predictionExplanation of TIGRFAM predictions
Accession Name Function Significance Role Sub Role Release No.
TIGR03566 FMN_reduc_MsuE FMN reductase 1.6e-120 No Data No Data 8.0
Pathways
Pathways Explanation of Pathways Field
Name Database Xref
Sulfur metabolism PseudoCAP
alkanesulfonate monooxygenase two-component system PseudoCyc ALKANEMONOX-PWY
Homology
BLINK Precomputed BLAST results at BLINK
Structure Features
PFAM predictions Explanation of PFAM predictions
Accession Domain Start Stop E-value Release No.
PF03358 FMN_red, NADPH-dependent FMN reductase. 6 141 1e-10 23.0
 
Genomic Context
Genomic context Explanation of Genomic Context Field - Part of msuEDC gene cluster.
Operons/Regulons
Type operon
Genes
GeneProduct
PA2354 probable transcriptional regulator
PA2355 probable FMNH2-dependent monooxygenase
msuD methanesulfonate sulfonatase MsuD
msuE NADH-dependent FMN reductase MsuE
Evidence Computationally Predicted
PubMed 18988623
Cross-Reference DOOR-13596
Microarray Expression Data
NCBI GEO Link
Sequence data
Upstream 500 BP Region CGGCCGCGCCGAGTCCGCCCGGTCCTCCAGTCACAGCAACCTTGGTTTCCCGACCCGGCGAAGAGGATCGCTGCATGCCGTACTGTTCGCCGGAACAACT CGCCGACCTCGGCCCGCTGCTGGATTGCCTGCGCCGCTGGCCGCGCATCCGCGAGCCGCGGCCTGGGGTGTTCTACCTGGGCGACCAGCCGTTCTGCCAG TTCCATTCGCGCAATGGCCAGCGCTGGGCCGACGTCAAGCGCCGCAAGGGGCGCCTGCCGCCGTTCGTCCTGCCGCCGGGCGACCAGCATTCGGCGCGGG CATTCCAGATATTCCTGCTCCAGGCCTACAAGCTGAACTGAACTGTTGCCCGGGCAACAGTCGGACAGCAGCGCTGTTGCGTGGCTGACAGGCCGAGGCC GGAAACCCGCCGCAACTGCCCGGAAAATGCACATTTCCCCGTTGGTACGGCCCTTGCTCCAGGGCACTGCACCTAGCGCAACAGTCCACAGGGAAATCCC

BLAST search against this genome or other genomes in database
Need more than 500 BP? Try our sequence retrieval tool or view intergenic regions in GBrowse.

DNA Sequence ATGACCAGCCCCTTCAAAGTCGTCGCCGTCTCCGGCGGCACCTATCGCCCGTCCCGCACCCTGGTACTCACCCAGGCCCTGATCGCCGAGCTTGGCCAGT CGTTGCCGATCGACAGCCGGGTCATCGAGCTGACCGACATCGCCGCGCCGCTGGGCGCTACCCTGGCGCGCAACCAGGCGCCGGCGGAACTGCAGGCGGT GCTCGACGAGATCGAAAGCGCCGACCTGCTGCTGGTCGCCTCGCCGGTCTACCGTGGCTCCTATCCGGGCCTGCTCAAGCACCTGTTCGACCTGATCGAC CTCAACGCCTTGATCGACACCCCGGTGCTGCTCGCCGCCACTGGCGGCACCGAGCGCCACGCGCTGGTCCTCGACCACCAGTTGCGCCCGCTGTTCAGCT TCTTCCAGGCGATCACCCTGCCCATCGGGGTCTACGCCAGCGAGGCCGACTTCGACAACTACCGGATCGTCAGCGAGCCGCTGAAGGCGCGCATCCGCCT CGCCGCCGAGCGCGCCGCGCCGCTGTTCGGCGGACGCTCCGAACTGTTGAAGATCGCCTGA

BLAST search against this genome or other genomes in database


Downstream 500 BP region Click here to view the nucleotide sequence of the region 500 BP downstream of this gene.

Protein Sequence MTSPFKVVAVSGGTYRPSRTLVLTQALIAELGQSLPIDSRVIELTDIAAPLGATLARNQAPAELQAVLDEIESADLLLVASPVYRGSYPGLLKHLFDLID LNALIDTPVLLAATGGTERHALVLDHQLRPLFSFFQAITLPIGVYASEADFDNYRIVSEPLKARIRLAAERAAPLFGGRSELLKIA

BLAST search against this genome or other genomes in database
View precomputed BLAST results against all genomes at NCBI BLINK
References
PubMed A novel reduced flavin mononucleotide-dependent methanesulfonate sulfonatase encoded by the sulfur-regulated msu operon of Pseudomonas aeruginosa.
Kertesz MA, Schmidt-Larbig K, Wuest T.
J Bacteriol. 1999 Mar;181(5):1464-73.
PMID: 10049377
 
Alternate Annotations and Cross-References
TIGR NTL03PA02357
Systomonas PA2357
RefSeq NP_251047.1
GI 15597553
KEGG PA2357
GBrowse Click here for a GBrowse View of this and other annotations.
PseudoCyc Click here to view metabolic pathways in PseudoCyc.


We thank Cystic Fibrosis Foundation Therapeutics, Inc. for critical funding support for the Pseudomonas Genome Database. When acknowledging use of the database, please cite the article by Winsor et al. (2009; PMID:18978025) and not the web site URL. Thank you!

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