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               PA3673               
Key to diagram


View in GBrowse: (?) 16 putative orthologs View metabolic pathways using PseudoCyc Acknowledgements for this annotation
Gene Information
Strain Pseudomonas aeruginosa PAO1 (Tax ID: 208964) Replicon Chromosome(5651 genes, 6264404 bp) [ RefSeq ]
Gene name plsB  Alternate Gene Names
Locus tag PA3673 (View 5 updates) GenBank Identifier (GI) 15598869 (Precomputed BLAST results at BLINK )
Genomic location 4112285 - 4114789 (+) Feature type CDS 
Transposon Mutant Available?Transposon mutant library help Yes (View in GBrowse) Pseudomonas Ortholog Group Explanation of Orthologous Groups
Product Information
Product Name glycerol-3-phosphate acyltransferase (Class 2  Explanation of Product Name Confidence)
Alternate Product Names
Subcellular localization
Function Classification / Gene Ontology (GO)
PseudoCAP Function Class Fatty acid and phospholipid metabolism
GO Accession GO Term Evidence
Molecular Function
GO:0004791 thioredoxin-disulfide reductase activity ISS
Biological Process
GO:0044255 cellular lipid metabolic process ISS
Cellular Component
COG PredictionExplanation of COG predictions
Accession Description Category
COG2937 PlsB, Glycerol-3-phosphate O-acyltransferase [Lipid metabolism]. Lipid metabolism
TIGRFAM predictionExplanation of TIGRFAM predictions
Accession Name Function Significance Role Sub Role Release No.
TIGR00530 AGP_acyltrn 1-acylglycerol-3-phosphate O-acyltransferases 1.1e-05 Fatty acid and phospholipid metabolism Biosynthesis 8.0
Pathways
Pathways Explanation of Pathways Field
Name Database Xref
Glycerolipid metabolism PseudoCAP
phospholipid biosynthesis PseudoCyc PHOSLIPSYN-PWY
Glycerolipid metabolism KEGG pae00561 Computationally Generated
Glycerophospholipid metabolism KEGG pae00564 Computationally Generated
Metabolic pathways KEGG pae01100 Computationally Generated
Reactions
EC Number 2.3.1.15
Homology
BLINK Precomputed BLAST results at BLINK
Homologs Explanation of Homologs Field 58% similar to E. coli PlsB, sn-glycerol-3-phosphate acyltransferase
Most Similar Human Homolog
ENSP00000355607, Percent Identity: 28.99%, E-Value: 2e-43, Ensembl Release: 56.
Description: Dihydroxyacetone phosphate acyltransferase
Structure Features
PFAM predictions Explanation of PFAM predictions
Accession Domain Start Stop E-value Release No.
PF01553 Acyltransferase, Acyltransferase. 298 429 9e-23 23.0
 
Microarray Expression Data
NCBI GEO Link
Sequence data
Upstream 500 BP Region GCGCCTGCAGCGTGCGGTTGCGGATGTCGAAGCCGAAAATGCTCGCGGTGCCGGCGCAGGGCGCCAGGAAGCCGGTGAGCATCTTCATGGTGGTGGACTT GCCGGCGCCGTTCGGACCGAGGAAGCCCAGTACCTCCCCCGTCTCCACCTGGAAGGACAGGTCGTCCACCGCCACCCGCGAGCCGAAGCGTTTGCCGAGG TTTCTTGTTTCGATCATGGTCCCCTACCTGTTCCGGCGGCCGCCGCCATGTCCGGCCAGGGCCGCGAAAAACGCGCAGGGACTATAGCCGAAGCGCCCCG CCGCCTGGCAATACGGGGCATCGGGAGAACCTTGGCAAAACGTGACAGAACCCGAACGCCTGCCGAAGGTTCTACATTCGCAACCTGTTCGCCGCCGTTC GCCGTAGGACGCGTTGCGTTCTTTTGCGGCCCTCCGGGGATTGCGGCAAACTAGCCGCGCCCGTCACGCCGGGTCCCGATCAACTGCCAGTAGACACCGT

BLAST search against this genome or other genomes in database
Need more than 500 BP? Try our sequence retrieval tool or view intergenic regions in GBrowse.

DNA Sequence ATGCCCCGCTACCCTTTCCGCCGCTTTGGTTTTGGCGCCCTGCGCCGCCTGCTGTACCTCTGGGTACGCTCGGAAACCATCAACCAATCGGCCTTCACCC TGAAGATCGACCGCAGCAAGCCGGTGCTCTACGTGCTGCAACAGCCTTCGGTCAGCGATCTCGCGGTAGTGGATACCGAATGCCGCAAGGCCGGGCTGCC GCGTCCGGTGATGCCGGTAGCGGTAGGCGACGCCATCGAGCCGGCGGCGTTCTTCTACCTGACGCCCGAACCCGACTGGCTCGGCCGCCAGGATAAGCGC GGCGCCTCGCCGACCCTGGTGCGCATGCTCGCCGCGGTCGGCCAGAACGGTCTCGACGACGCGCAGATCATTCCGGTCAGCGTGTTCTGGGGACAATCGC CGGACAGCGAATCGAGCCCCTGGAAGCTGCTGTTCGCCGACAACTGGGCGGTCACCGGGCGCCTGCGCAAGCTGGCGCGCATCCTGATCCTCGGACGCAA GACCCGTGTGCAGTTCTCCGCGCCGATCCACCTGCGCGAGCTGGTGGAACAGGGCAAGGGCCACGAGCGCACGCTGCGCATGGTCAACCGTATCCTCCGG GTGCACTTCCGCAACCTGAAGACCGCGGTGATCGGTCCCGACCTGTCGCACCGCCGCAACCTGGTCAAGGGCCTGCTGCGCGCGCCGCTGGTACGCCAGG CGATCAGCGAGGAATGCGAGAGCGAACGGATATCCCAGGAAAAGGCCGAAGGCATCGCACTGCGCTACGCCAATGAAATCGCCTCGGACTTCTCCTATCC GGTGATCCGCTTCCTCGAAGTCATCCTCAGCTGGTTCTGGAACAAGCTGTACGAAGGGGTCAAGGTCAACCACATCGAGCGGGTGCAGGACGTGGCCCAG GGCAACGAGATCGTCTACGTGCCCTGCCACCGCAGCCACATCGACTACCTGCTGCTCTCCTACCTGCTGTTCCGCAACGGCCTGACCCCGCCGCACATCG CCGCCGGGATCAACCTGAACATGCCGGTGATCGGCTCGATCCTGCGCCGCGGCGGGGCCTTCTTCATGCGCCGCAGCTTCAAGGGCAACCAGCTCTACAC CGCGGTGTTCAACGAGTACCTGCACACCCTGTTCTCCCGCGGCTTCTCCACCGAGTACTTCGTCGAGGGCGGCCGTTCGCGCACCGGGCGCATGCTCCAC CCACGCACCGGCATGCTCGCCATCACCCTGCGCAGCTTCCTCCGTGACTCGCGCCGGCCGATCGTCTTCGTGCCGGTCTACATCGGCTACGAGCGCGTGC TGGAAGGCCGCACCTACCTCGGCGAACTGCGCGGCGCGACCAAGAAGAAGGAGTCGATCTTCGACCTGTTCAAGGTGGTCGGCGCCCTGAAGCAGCGTTT TGGCCAGGTCTGGGTGAACTTCGGCGAGCCGATCCATCTCGACCAGTTCCTCGACCGCCACCAGCCCGACTGGCAGGACCAGGACCTCGGCCCGGAATAC CGCCCCGACTGGCTGCCGCAGACCACCAACCTGCTGGCCAAGGACGTCGCCCGCCACCTCAACGACGCGGCGGCGATCAACCCGGTCAACCTGGTCGCCC TGGCGCTGCTCTCCACCAGCCGCCAGGCCCTCGACGAAAGCGCCCTGGCGCGAATCCTCGACCTCTACCTGGCGTTGCTGCGCAAGGTGCCCTACTCGCC CAGCGCGACCCTGCCGGACGGCGACGGCCAGGCCCTGATCGAATACGTGAAGAGCATGAACCTGCTGGCCGAGCAGAAGGACGCGCTGGGCCGCATCCTC TATCTCGACGAACAGAACGCGGTGCTGGCGACCTACTACCGCAACAACGTCCTCCACGTCTTCGCCCTGCCGGCGCTGATCGCCAGCTTCTTCCAGAGCA ACTCGCGGATCAGCCGCGAACAGTTGCTGCGCTTCGCCCGCGCGCTCTATCCCTACCTGCAGGCGGAACTGTTCATCCGCTGGAGCCTGGACGAACTCGA CGCGGTGATCGACCAGTGGCTGGCGGCCCTGGTGGAACAGGACCTGCTGCGCCAGGAGAACGACACCTTCATCCGCCCGGCGCCAAGCTCGCGGCAATAT GTGCTGCTGATCCTCCTCGCTCGTTCGGTGACCCAGACCCTGCAGCGCTTCTACATGGCCATCGCCCTGCTGCTCAACGCCGGGCAGAACGCCCTGACCG CCGAGGAACTGGAGAACCTCTGCACCGTGATGGCCCAGCGCCTGTCGATCCTGCATGGCCTGAACGCCCCGGAGTTCTTCGACAAGAGCCTGTTCCGCCA CTTCATCCAGACCCTTCTCGACCTGCGCGTGCTGCGCAAGGACGAGGCCGGCAAGCTGAGCTACCACGAACTGCTCGGCGAACTGGCCGAAGGCGCCGCC AAGCGCGTGCTGCCGGCGGAGATCCGTCTGTCGATCCGCCAGGTGGCGCTGGAGCGCCCCGCCGAGGAAGCCGCCGCCGAAAGCAACGACGCGGCCGCCA ACTGA

BLAST search against this genome or other genomes in database


Downstream 500 BP region Click here to view the nucleotide sequence of the region 500 BP downstream of this gene.

Protein Sequence MPRYPFRRFGFGALRRLLYLWVRSETINQSAFTLKIDRSKPVLYVLQQPSVSDLAVVDTECRKAGLPRPVMPVAVGDAIEPAAFFYLTPEPDWLGRQDKR GASPTLVRMLAAVGQNGLDDAQIIPVSVFWGQSPDSESSPWKLLFADNWAVTGRLRKLARILILGRKTRVQFSAPIHLRELVEQGKGHERTLRMVNRILR VHFRNLKTAVIGPDLSHRRNLVKGLLRAPLVRQAISEECESERISQEKAEGIALRYANEIASDFSYPVIRFLEVILSWFWNKLYEGVKVNHIERVQDVAQ GNEIVYVPCHRSHIDYLLLSYLLFRNGLTPPHIAAGINLNMPVIGSILRRGGAFFMRRSFKGNQLYTAVFNEYLHTLFSRGFSTEYFVEGGRSRTGRMLH PRTGMLAITLRSFLRDSRRPIVFVPVYIGYERVLEGRTYLGELRGATKKKESIFDLFKVVGALKQRFGQVWVNFGEPIHLDQFLDRHQPDWQDQDLGPEY RPDWLPQTTNLLAKDVARHLNDAAAINPVNLVALALLSTSRQALDESALARILDLYLALLRKVPYSPSATLPDGDGQALIEYVKSMNLLAEQKDALGRIL YLDEQNAVLATYYRNNVLHVFALPALIASFFQSNSRISREQLLRFARALYPYLQAELFIRWSLDELDAVIDQWLAALVEQDLLRQENDTFIRPAPSSRQY VLLILLARSVTQTLQRFYMAIALLLNAGQNALTAEELENLCTVMAQRLSILHGLNAPEFFDKSLFRHFIQTLLDLRVLRKDEAGKLSYHELLGELAEGAA KRVLPAEIRLSIRQVALERPAEEAAAESNDAAAN

BLAST search against this genome or other genomes in database
View precomputed BLAST results against all genomes at NCBI BLINK
References
PubMed Partial NH2- and COOH-terminal sequence and cyanogen bromide peptide analysis of Escherichia coli sn-glycerol-3-phosphate acyltransferase.
Green PR, Vanaman TC, Modrich P, Bell RM.
J Biol Chem. 1983 Sep 25;258(18):10862-6.
PMID: 6350296
 
Alternate Annotations and Cross-References
TIGR NTL03PA03673
Systomonas PA3673
RefSeq NP_252363.1
GI 15598869
KEGG PA3673
GBrowse Click here for a GBrowse View of this and other annotations.
PseudoCyc Click here to view metabolic pathways in PseudoCyc.


We thank Cystic Fibrosis Foundation Therapeutics, Inc. for critical funding support for the Pseudomonas Genome Database. When acknowledging use of the database, please cite the article by Winsor et al. (2009; PMID:18978025) and not the web site URL. Thank you!

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