Ontology | Accession | Term | GO Evidence | Evidence Ontology (ECO) Code | Reference | Comments |
---|---|---|---|---|---|---|
Biological Process | GO:0046654 | tetrahydrofolate biosynthetic process |
Inferred from Sequence Model
Term mapped from: InterPro:PF00186
|
ECO:0000259 match to InterPro signature evidence used in automatic assertion |
||
Molecular Function | GO:0050661 | NADP binding |
Inferred from Sequence Model
Term mapped from: InterPro:PIRSF000194
|
ECO:0000259 match to InterPro signature evidence used in automatic assertion |
||
Molecular Function | GO:0004146 | dihydrofolate reductase activity |
Inferred from Sequence Model
Term mapped from: InterPro:PF00186
|
ECO:0000259 match to InterPro signature evidence used in automatic assertion |
||
Biological Process | GO:0006545 | glycine biosynthetic process |
Inferred from Sequence Model
Term mapped from: InterPro:PIRSF000194
|
ECO:0000259 match to InterPro signature evidence used in automatic assertion |
|
Database | Xref | Pathway | Version | Evidence | PMID |
---|---|---|---|---|---|
PseudoCAP | Folate biosynthesis |
ECO:0000037
not_recorded |
|||
KEGG | pae01100 | Metabolic pathways | 81.0+/01-23, Jan 17 |
ECO:0000249
sequence similarity evidence used in automatic assertion |
|
PseudoCyc | 1CMET2-PWY | N<sup>10</sup>-formyl-tetrahydrofolate biosynthesis | 19.5 |
ECO:0000250
sequence similarity evidence used in manual assertion |
12867747 |
PseudoCyc | ALL-CHORISMATE-PWY | superpathway of chorismate metabolism | 19.5 |
ECO:0000250
sequence similarity evidence used in manual assertion |
12867747 |
PseudoCyc | PWY-6614 | tetrahydrofolate biosynthesis | 19.5 |
ECO:0000250
sequence similarity evidence used in manual assertion |
12867747 |
KEGG | pae00790 | Folate biosynthesis | 81.0+/01-23, Jan 17 |
ECO:0000249
sequence similarity evidence used in automatic assertion |
|
PseudoCAP | One carbon pool by folate |
ECO:0000037
not_recorded |
|||
PseudoCyc | PWY-6612 | superpathway of tetrahydrofolate biosynthesis | 19.5 |
ECO:0000250
sequence similarity evidence used in manual assertion |
12867747 |
KEGG | pae00670 | One carbon pool by folate | 81.0+/01-23, Jan 17 |
ECO:0000249
sequence similarity evidence used in automatic assertion |
Analysis | Accession | Description | Interpro Accession | Interpro Description | Amino Acid Start | Amino Acid Stop | E-value |
---|---|---|---|---|---|---|---|
SUPERFAMILY | SSF53597 | Dihydrofolate reductase-like | IPR024072 | Dihydrofolate reductase-like domain superfamily | 4 | 168 | 2.11E-55 |
PRINTS | PR00070 | Dihydrofolate reductase signature | - | - | 30 | 38 | 6.8E-16 |
PIRSF | PIRSF000194 | DHFR | IPR012259 | Dihydrofolate reductase | 1 | 168 | 1.6E-58 |
PRINTS | PR00070 | Dihydrofolate reductase signature | - | - | 16 | 26 | 6.8E-16 |
Gene3D | G3DSA:3.40.430.10 | Dihydrofolate Reductase, subunit A | IPR024072 | Dihydrofolate reductase-like domain superfamily | 4 | 168 | 6.9E-56 |
PRINTS | PR00070 | Dihydrofolate reductase signature | - | - | 100 | 114 | 6.8E-16 |
PRINTS | PR00070 | Dihydrofolate reductase signature | - | - | 43 | 54 | 6.8E-16 |
Pfam | PF00186 | Dihydrofolate reductase | IPR001796 | Dihydrofolate reductase domain | 5 | 167 | 1.2E-54 |
PANTHER | PTHR48069 | DIHYDROFOLATE REDUCTASE | IPR012259 | Dihydrofolate reductase | 5 | 166 | 4.1E-37 |
FunFam | G3DSA:3.40.430.10:FF:000001 | Dihydrofolate reductase | - | - | 3 | 168 | 3.3E-61 |
CDD | cd00209 | DHFR | IPR001796 | Dihydrofolate reductase domain | 5 | 151 | 1.36152E-69 |