Pseudomonas aeruginosa PAO1, PA1010 (dapA)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse PseudoCyc / Metabolic Pathways

Gene Ontology

Ontology Accession Term GO Evidence Evidence Ontology (ECO) Code Reference Comments
Biological Process GO:0009085 lysine biosynthetic process
ISS
Inferred from Sequence or Structural Similarity
ECO:0000044
sequence similarity evidence
Biological Process GO:0006520 cellular amino acid metabolic process
ISS
Inferred from Sequence or Structural Similarity
ECO:0000044
sequence similarity evidence
Molecular Function GO:0003855 3-dehydroquinate dehydratase activity
ISS
Inferred from Sequence or Structural Similarity
ECO:0000044
sequence similarity evidence
Molecular Function GO:0016829 lyase activity
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PTHR12128
ECO:0000259
match to InterPro signature evidence used in automatic assertion
Biological Process GO:0009089 lysine biosynthetic process via diaminopimelate
ISM
Inferred from Sequence Model
Term mapped from: InterPro:cd00950
ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0008840 4-hydroxy-tetrahydrodipicolinate synthase activity
ISM
Inferred from Sequence Model
Term mapped from: InterPro:cd00950
ECO:0000259
match to InterPro signature evidence used in automatic assertion

Functional Classifications Manually Assigned by PseudoCAP

Amino acid biosynthesis and metabolism Other PAO1 genes in this class

Pathways

Database Xref Pathway Version Evidence PMID
KEGG pae00300 Lysine biosynthesis 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion
PseudoCAP Lysine biosynthesis ECO:0000037
not_recorded
KEGG pae01130 Biosynthesis of antibiotics 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion
KEGG pae01120 Microbial metabolism in diverse environments 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion
PseudoCyc P4-PWY superpathway of L-lysine, L-threonine and L-methionine biosynthesis I 19.5 ECO:0000250
sequence similarity evidence used in manual assertion
12867747
KEGG pae01100 Metabolic pathways 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion
PseudoCyc DAPLYSINESYN-PWY L-lysine biosynthesis I 19.5 ECO:0000250
sequence similarity evidence used in manual assertion
12867747
KEGG pae01110 Biosynthesis of secondary metabolites 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion
KEGG pae00261 Monobactam biosynthesis 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion
KEGG pae01230 Biosynthesis of amino acids 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion

Functional Predictions from Interpro

Analysis Accession Description Interpro Accession Interpro Description Amino Acid Start Amino Acid Stop E-value
CDD cd00950 DHDPS IPR005263 4-hydroxy-tetrahydrodipicolinate synthase, DapA 4 285 0.0
Hamap MF_00418 4-hydroxy-tetrahydrodipicolinate synthase [dapA]. IPR005263 4-hydroxy-tetrahydrodipicolinate synthase, DapA 1 287 69.373184
SUPERFAMILY SSF51569 Aldolase - - 2 289 3.87E-107
PRINTS PR00146 Dihydrodipicolinate synthase signature IPR002220 DapA-like 35 56 8.9E-35
PRINTS PR00146 Dihydrodipicolinate synthase signature IPR002220 DapA-like 128 145 8.9E-35
Pfam PF00701 Dihydrodipicolinate synthetase family IPR002220 DapA-like 2 285 1.7E-109
PIRSF PIRSF001365 DHDPS IPR002220 DapA-like 1 292 1.9E-100
NCBIfam TIGR00674 JCVI: 4-hydroxy-tetrahydrodipicolinate synthase IPR005263 4-hydroxy-tetrahydrodipicolinate synthase, DapA 5 286 3.3E-115
Gene3D G3DSA:3.20.20.70 Aldolase class I IPR013785 Aldolase-type TIM barrel 1 291 9.8E-111
SMART SM01130 DHDPS_2 IPR002220 DapA-like 1 289 0.0
PANTHER PTHR12128 DIHYDRODIPICOLINATE SYNTHASE IPR002220 DapA-like 3 290 1.0E-81
PRINTS PR00146 Dihydrodipicolinate synthase signature IPR002220 DapA-like 103 119 8.9E-35
Coils Coil Coil - - 160 180 -
PRINTS PR00146 Dihydrodipicolinate synthase signature IPR002220 DapA-like 71 89 8.9E-35

Search for additional functional domains at the NCBI CDD database website. Go to this protein's amino acid sequence and follow the link.