Pseudomonas aeruginosa PAO1, PA1273 (cobB)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse PseudoCyc / Metabolic Pathways

Gene Ontology

Ontology Accession Term GO Evidence Evidence Ontology (ECO) Code Reference Comments
Biological Process GO:0051188 obsolete cofactor biosynthetic process
ISS
Inferred from Sequence or Structural Similarity
ECO:0000044
sequence similarity evidence
Molecular Function GO:0042242 cobyrinic acid a,c-diamide synthase activity
ISM
Inferred from Sequence Model
Term mapped from: InterPro:MF_00027
ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0003824 catalytic activity
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PF07685
ECO:0000259
match to InterPro signature evidence used in automatic assertion

Functional Classifications Manually Assigned by PseudoCAP

Biosynthesis of cofactors, prosthetic groups and carriers Other PAO1 genes in this class

Pathways

Database Xref Pathway Version Evidence PMID
PseudoCAP Cobalamin biosynthesis ECO:0000037
not_recorded
KEGG pae01100 Metabolic pathways 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion
PseudoCyc P381-PWY adenosylcobalamin biosynthesis II (late cobalt incorporation) 19.5 ECO:0000250
sequence similarity evidence used in manual assertion
12867747
PseudoCyc PWY-7376 cob(II)yrinate a,c-diamide biosynthesis II (late cobalt incorporation) 19.5 ECO:0000250
sequence similarity evidence used in manual assertion
12867747
KEGG pae00860 Porphyrin and chlorophyll metabolism 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion

Functional Predictions from Interpro

Analysis Accession Description Interpro Accession Interpro Description Amino Acid Start Amino Acid Stop E-value
CDD cd03130 GATase1_CobB - - 240 421 3.05261E-73
PANTHER PTHR43873 COBYRINATE A,C-DIAMIDE SYNTHASE IPR004484 Cobyrinic acid a,c-diamide synthase CbiA 7 432 1.2E-124
Hamap MF_00027 Hydrogenobyrinate a,c-diamide synthase [cobB]. IPR004484 Cobyrinic acid a,c-diamide synthase CbiA 6 421 39.236717
SUPERFAMILY SSF52540 P-loop containing nucleoside triphosphate hydrolases IPR027417 P-loop containing nucleoside triphosphate hydrolase 8 194 1.77E-40
Gene3D G3DSA:3.40.50.300 - IPR027417 P-loop containing nucleoside triphosphate hydrolase 45 182 1.7E-10
NCBIfam TIGR00379 JCVI: hydrogenobyrinic acid a,c-diamide synthase (glutamine-hydrolyzing) IPR004484 Cobyrinic acid a,c-diamide synthase CbiA 10 430 7.9E-82
SUPERFAMILY SSF52317 Class I glutamine amidotransferase-like IPR029062 Class I glutamine amidotransferase-like 235 428 1.92E-31
CDD cd05388 CobB_N - - 7 191 2.01063E-84
Pfam PF07685 CobB/CobQ-like glutamine amidotransferase domain IPR011698 CobB/CobQ-like glutamine amidotransferase 239 418 4.1E-31
Gene3D G3DSA:3.40.50.880 - IPR029062 Class I glutamine amidotransferase-like 236 414 5.3E-11
Pfam PF01656 CobQ/CobB/MinD/ParA nucleotide binding domain IPR002586 CobQ/CobB/MinD/ParA nucleotide binding domain 9 187 1.2E-12

Search for additional functional domains at the NCBI CDD database website. Go to this protein's amino acid sequence and follow the link.