Pseudomonas aeruginosa PAO1, PA1919 (nrdG)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse PseudoCyc / Metabolic Pathways

Gene Ontology

Ontology Accession Term GO Evidence Evidence Ontology (ECO) Code Reference Comments
Molecular Function GO:0004748 ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor
ISS
Inferred from Sequence or Structural Similarity
Term mapped from: UniProtKB:P0A9N8
 ECO:0000250
sequence similarity evidence used in manual assertion		 8954104 Reviewed by curator
Molecular Function GO:0003824 catalytic activity
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PF04055
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0051536 iron-sulfur cluster binding
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PF04055
 ECO:0000259
match to InterPro signature evidence used in automatic assertion

Functional Classifications Manually Assigned by PseudoCAP

Nucleotide biosynthesis and metabolism Other PAO1 genes in this class

Pathways

Database Xref Pathway Version Evidence PMID
PseudoCAP Purine metabolism ECO:0000037
not_recorded

Functional Predictions from Interpro

Analysis Accession Description Interpro Accession Interpro Description Amino Acid Start Amino Acid Stop E-value
Gene3D G3DSA:3.20.20.70 Aldolase class I IPR013785 Aldolase-type TIM barrel 5 206 1.4E-29
SFLD SFLDS00029 Radical SAM IPR007197 Radical SAM 4 207 0.0
NCBIfam TIGR02495 JCVI: anaerobic ribonucleoside-triphosphate reductase activating protein IPR012840 Anaerobic ribonucleoside-triphosphate reductase activating protein 7 194 4.5E-72
Pfam PF04055 Radical SAM superfamily IPR007197 Radical SAM 27 160 1.4E-13
CDD cd01335 Radical_SAM - - 25 222 2.79561E-11
SFLD SFLDG01094 Uncharacterised Radical SAM Subgroup 6 IPR012840 Anaerobic ribonucleoside-triphosphate reductase activating protein 4 207 0.0
Pfam PF13353 4Fe-4S single cluster domain - - 23 83 1.3E-7
PANTHER PTHR30352 PYRUVATE FORMATE-LYASE-ACTIVATING ENZYME IPR034457 Organic radical-activating enzymes 12 197 1.1E-23
SUPERFAMILY SSF102114 Radical SAM enzymes - - 18 196 4.19E-19

Search for additional functional domains at the NCBI CDD database website. Go to this protein's amino acid sequence and follow the link.