Pseudomonas aeruginosa PAO1, PA1920 (nrdD)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse PseudoCyc / Metabolic Pathways

Gene Ontology

Ontology Accession Term GO Evidence Evidence Ontology (ECO) Code Reference Comments
Molecular Function GO:0004748 ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor
ISS
Inferred from Sequence or Structural Similarity
Term mapped from: UniProtKB:P28903
 ECO:0000250
sequence similarity evidence used in manual assertion		 8954104 Reviewed by curator
Biological Process GO:0009405 pathogenesis
IMP
Inferred from Mutant Phenotype 		ECO:0000016
loss-of-function mutant phenotype evidence		 17481950 Reviewed by curator
Biological Process GO:0006260 DNA replication
ISM
Inferred from Sequence Model
Term mapped from: InterPro:cd01675
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0008998 ribonucleoside-triphosphate reductase activity
ISM
Inferred from Sequence Model
Term mapped from: InterPro:cd01675
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0016491 oxidoreductase activity
ISM
Inferred from Sequence Model
Term mapped from: InterPro:cd01675
 ECO:0000259
match to InterPro signature evidence used in automatic assertion

Functional Classifications Manually Assigned by PseudoCAP

Nucleotide biosynthesis and metabolism Other PAO1 genes in this class

Pathways

Database Xref Pathway Version Evidence PMID
PseudoCAP Pyrimidine metabolism ECO:0000037
not_recorded
KEGG pae01100 Metabolic pathways 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion
KEGG pae00240 Pyrimidine metabolism 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion
KEGG pae00230 Purine metabolism 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion
PseudoCAP Purine metabolism ECO:0000037
not_recorded

Functional Predictions from Interpro

Analysis Accession Description Interpro Accession Interpro Description Amino Acid Start Amino Acid Stop E-value
SUPERFAMILY SSF51998 PFL-like glycyl radical enzymes - - 127 660 0.0
Pfam PF03477 ATP cone domain IPR005144 ATP-cone domain 14 96 4.7E-20
NCBIfam TIGR02487 JCVI: anaerobic ribonucleoside-triphosphate reductase IPR012833 Ribonucleoside-triphosphate reductase, anaerobic 126 659 0.0
FunFam G3DSA:3.20.70.20:FF:000024 Anaerobic ribonucleoside triphosphate reductase - - 140 665 0.0
PANTHER PTHR21075 ANAEROBIC RIBONUCLEOSIDE-TRIPHOSPHATE REDUCTASE - - 13 660 0.0
Pfam PF13597 Anaerobic ribonucleoside-triphosphate reductase IPR012833 Ribonucleoside-triphosphate reductase, anaerobic 127 658 0.0
Gene3D G3DSA:3.20.70.20 - - - 140 665 0.0
CDD cd01675 RNR_III IPR012833 Ribonucleoside-triphosphate reductase, anaerobic 126 675 0.0

Search for additional functional domains at the NCBI CDD database website. Go to this protein's amino acid sequence and follow the link.