Pseudomonas aeruginosa PAO1, PA1987 (pqqC)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse PseudoCyc / Metabolic Pathways

Gene Feature Overview

Strain Pseudomonas aeruginosa PAO1 (Stover et al., 2000)
GCF_000006765.1|latest
Locus Tag
PA1987
Name
pqqC
Replicon chromosome
Genomic location 2172913 - 2173665 (+ strand)
Transposon Mutants in orthologs 2 transposon mutants in orthologs

Cross-References

RefSeq NP_250677.1
GI 15597183
Affymetrix PA1987_pqqC_at
Entrez 879112
GenBank AAG05375.1
INSDC AAG05375.1
NCBI Locus Tag PA1987
protein_id(GenBank) gb|AAG05375.1|AE004625_5|gnl|PseudoCAP|PA1987
TIGR NTL03PA01987
UniParc UPI00000C5543
UniProtKB Acc Q9I2C2
UniProtKB ID PQQC_PSEAE
UniRef100 UniRef100_B7VAB8
UniRef50 UniRef50_P07780
UniRef90 UniRef90_B7VAB8

Product

Feature Type CDS
Coding Frame 1
Product Name
pyrroloquinoline quinone biosynthesis protein C
Product Name Confidence: Class 2
Synonyms coenzyme PQQ synthesis protein C
Evidence for Translation
Charge (pH 7) 1.62
Kyte-Doolittle Hydrophobicity Value -0.571
Molecular Weight (kDa) 29.4
Isoelectric Point (pI) 7.43

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 100 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG003446 (525 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA1987
Search term: pqqC

Human Homologs

References

Acinetobacter calcoaceticus genes involved in biosynthesis of the coenzyme pyrrolo-quinoline-quinone: nucleotide sequence and expression in Escherichia coli K-12.
Goosen N, Horsman HP, Huinen RG, van de Putte P
J Bacteriol 1989 Jan;171(1):447-55
PubMed ID: 2536663
Nucleotide sequence and structure of the Klebsiella pneumoniae pqq operon.
Meulenberg JJ, Sellink E, Riegman NH, Postma PW
Mol Gen Genet 1992 Mar;232(2):284-94
PubMed ID: 1313537
Synthesis of pyrroloquinoline quinone in vivo and in vitro and detection of an intermediate in the biosynthetic pathway.
Velterop JS, Sellink E, Meulenberg JJ, David S, Bulder I, Postma PW
J Bacteriol 1995 Sep;177(17):5088-98
PubMed ID: 7665488