Pseudomonas aeruginosa PAO1, PA4047 (ribA)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse PseudoCyc / Metabolic Pathways

Gene Ontology

Ontology Accession Term GO Evidence Evidence Ontology (ECO) Code Reference Comments
Biological Process GO:0009231 riboflavin biosynthetic process
ISS
Inferred from Sequence or Structural Similarity 		ECO:0000250
sequence similarity evidence used in manual assertion		 9574900 Reviewed by curator
Biological Process GO:0051188 obsolete cofactor biosynthetic process
ISS
Inferred from Sequence or Structural Similarity 		ECO:0000044
sequence similarity evidence
Molecular Function GO:0003935 GTP cyclohydrolase II activity
ISM
Inferred from Sequence Model
Term mapped from: InterPro:cd00641
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Biological Process GO:0009231 riboflavin biosynthetic process
ISM
Inferred from Sequence Model
Term mapped from: InterPro:cd00641
 ECO:0000259
match to InterPro signature evidence used in automatic assertion

Functional Classifications Manually Assigned by PseudoCAP

Biosynthesis of cofactors, prosthetic groups and carriers Other PAO1 genes in this class

Pathways

Database Xref Pathway Version Evidence PMID
KEGG pae01110 Biosynthesis of secondary metabolites 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion
PseudoCyc RIBOSYN2-PWY flavin biosynthesis I (bacteria and plants) 19.5 ECO:0000250
sequence similarity evidence used in manual assertion 		12867747
KEGG pae01100 Metabolic pathways 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion
KEGG pae00740 Riboflavin metabolism 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion
KEGG pae02024 Quorum sensing 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion
PseudoCAP Riboflavin metabolism ECO:0000037
not_recorded

Functional Predictions from Interpro

Analysis Accession Description Interpro Accession Interpro Description Amino Acid Start Amino Acid Stop E-value
NCBIfam TIGR00505 JCVI: GTP cyclohydrolase II IPR000926 GTP cyclohydrolase II, RibA 7 194 4.3E-80
Gene3D G3DSA:3.40.50.10990 GTP cyclohydrolase II IPR036144 GTP cyclohydrolase II superfamily 2 172 7.8E-72
Pfam PF00925 GTP cyclohydrolase II IPR032677 GTP cyclohydrolase II 8 170 5.8E-67
CDD cd00641 GTP_cyclohydro2 IPR000926 GTP cyclohydrolase II, RibA 2 194 1.13701E-114
SUPERFAMILY SSF142695 RibA-like IPR036144 GTP cyclohydrolase II superfamily 3 172 1.57E-65
PANTHER PTHR21327 GTP CYCLOHYDROLASE II-RELATED - - 3 195 1.8E-80
Hamap MF_00179 GTP cyclohydrolase-2 [ribA]. IPR000926 GTP cyclohydrolase II, RibA 1 196 45.259384
FunFam G3DSA:3.40.50.10990:FF:000002 GTP cyclohydrolase-2 - - 1 174 5.2E-85

Search for additional functional domains at the NCBI CDD database website. Go to this protein's amino acid sequence and follow the link.