Pseudomonas aeruginosa PAO1, PA4938 (purA)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse PseudoCyc / Metabolic Pathways

Gene Ontology

Ontology Accession Term GO Evidence Evidence Ontology (ECO) Code Reference Comments
Biological Process GO:0009117 nucleotide metabolic process
ISS
Inferred from Sequence or Structural Similarity 		ECO:0000044
sequence similarity evidence
Biological Process GO:0006531 aspartate metabolic process
ISS
Inferred from Sequence or Structural Similarity 		ECO:0000044
sequence similarity evidence
Molecular Function GO:0004077 biotin-[acetyl-CoA-carboxylase] ligase activity
ISS
Inferred from Sequence or Structural Similarity 		ECO:0000044
sequence similarity evidence
Biological Process GO:0006522 alanine metabolic process
ISS
Inferred from Sequence or Structural Similarity 		ECO:0000044
sequence similarity evidence
Biological Process GO:0006163 purine nucleotide metabolic process
ISS
Inferred from Sequence or Structural Similarity 		ECO:0000044
sequence similarity evidence
Biological Process GO:0006520 cellular amino acid metabolic process
ISS
Inferred from Sequence or Structural Similarity 		ECO:0000044
sequence similarity evidence
Biological Process GO:0006164 purine nucleotide biosynthetic process
ISM
Inferred from Sequence Model
Term mapped from: InterPro:MF_00011
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0004019 adenylosuccinate synthase activity
ISM
Inferred from Sequence Model
Term mapped from: InterPro:MF_00011
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0000166 nucleotide binding
ISM
Inferred from Sequence Model
Term mapped from: InterPro:MF_00011
 ECO:0000259
match to InterPro signature evidence used in automatic assertion

Functional Classifications Manually Assigned by PseudoCAP

Nucleotide biosynthesis and metabolism Other PAO1 genes in this class
Amino acid biosynthesis and metabolism Other PAO1 genes in this class

Pathways

Database Xref Pathway Version Evidence PMID
PseudoCAP Alanine and Aspartate metabolism ECO:0000037
not_recorded
KEGG pae00250 Alanine, aspartate and glutamate metabolism 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion
KEGG pae00230 Purine metabolism 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion
PseudoCyc PWY-7219 adenosine ribonucleotides de novo biosynthesis 19.5 ECO:0000250
sequence similarity evidence used in manual assertion 		12867747
PseudoCAP Purine metabolism ECO:0000037
not_recorded
KEGG pae01100 Metabolic pathways 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion

Functional Predictions from Interpro

Analysis Accession Description Interpro Accession Interpro Description Amino Acid Start Amino Acid Stop E-value
SMART SM00788 adenylsucc_synt IPR001114 Adenylosuccinate synthetase 4 424 0.0
Gene3D G3DSA:3.40.440.10 Adenylosuccinate Synthetase, subunit A, domain 1 IPR042109 Adenylosuccinate synthetase, domain 1 6 257 2.4E-115
Gene3D G3DSA:3.90.170.10 Adenylosuccinate Synthetase, subunit A, domain 3 IPR042111 Adenylosuccinate synthetase, domain 3 267 430 8.1E-69
NCBIfam TIGR00184 JCVI: adenylosuccinate synthase IPR001114 Adenylosuccinate synthetase 6 429 0.0
PANTHER PTHR11846 ADENYLOSUCCINATE SYNTHETASE IPR001114 Adenylosuccinate synthetase 4 423 0.0
Pfam PF00709 Adenylosuccinate synthetase IPR001114 Adenylosuccinate synthetase 6 423 0.0
Gene3D G3DSA:1.10.300.10 Adenylosuccinate Synthetase, subunit A, domain 2 IPR042110 Adenylosuccinate synthetase, domain 2 102 201 2.4E-115
FunFam G3DSA:3.90.170.10:FF:000001 Adenylosuccinate synthetase - - 267 429 1.3E-68
CDD cd03108 AdSS IPR001114 Adenylosuccinate synthetase 3 424 0.0
Hamap MF_00011 Adenylosuccinate synthetase [purA]. IPR001114 Adenylosuccinate synthetase 1 430 218.941818
SUPERFAMILY SSF52540 P-loop containing nucleoside triphosphate hydrolases IPR027417 P-loop containing nucleoside triphosphate hydrolase 3 429 0.0
FunFam G3DSA:1.10.300.10:FF:000001 Adenylosuccinate synthetase - - 102 201 4.6E-37

Search for additional functional domains at the NCBI CDD database website. Go to this protein's amino acid sequence and follow the link.