Pseudomonas aeruginosa PAO1, PA5017 (dipA)

Gene Ontology

Ontology	Accession	Term	GO Evidence	Evidence Ontology (ECO) Code	Reference	Comments
Biological Process	GO:0009405	pathogenesis	IMP Inferred from Mutant Phenotype	ECO:0000315 mutant phenotype evidence used in manual assertion	24901523	Reviewed by curator
Molecular Function	GO:0071111	cyclic-guanylate-specific phosphodiesterase activity	IDA Inferred from Direct Assay	ECO:0000005 enzyme assay evidence	22493016	Reviewed by curator
Biological Process	GO:0043200	response to amino acid	IMP Inferred from Mutant Phenotype	ECO:0000016 loss-of-function mutant phenotype evidence	22493016	Reviewed by curator
Molecular Function	GO:0005515	protein binding	ISM Inferred from Sequence Model Term mapped from: InterPro:SM00065	ECO:0000259 match to InterPro signature evidence used in automatic assertion

Functional Classifications Manually Assigned by PseudoCAP

Hypothetical, unclassified, unknown Other PAO1 genes in this class

Functional Predictions from Interpro

Analysis	Accession	Description	Interpro Accession	Interpro Description	Amino Acid Start	Amino Acid Stop	E-value
Pfam	PF00990	Diguanylate cyclase, GGDEF domain	IPR000160	GGDEF domain	471	624	1.7E-39
SUPERFAMILY	SSF55781	GAF domain-like	-	-	195	335	1.92E-19
FunFam	G3DSA:3.20.20.450:FF:000001	Cyclic di-GMP phosphodiesterase yahA	-	-	640	894	1.9E-101
CDD	cd00130	PAS	IPR000014	PAS domain	355	457	4.55291E-11
SMART	SM00091	pas_2	IPR000014	PAS domain	24	87	59.0
Gene3D	G3DSA:3.20.20.450	EAL domain	IPR035919	EAL domain superfamily	642	894	1.2E-103
NCBIfam	TIGR00229	JCVI: PAS domain S-box protein	IPR000014	PAS domain	346	466	3.9E-17
PANTHER	PTHR44757	DIGUANYLATE CYCLASE DGCP	-	-	134	885	0.0
Gene3D	G3DSA:3.30.450.40	-	IPR029016	GAF-like domain superfamily	166	342	3.7E-18
SMART	SM00065	gaf_1	IPR003018	GAF domain	192	343	8.6E-9
CDD	cd01948	EAL	IPR001633	EAL domain	645	884	3.60625E-103
SMART	SM00267	duf1_3	IPR000160	GGDEF domain	460	629	1.7E-56
SMART	SM00086	pac_2	IPR001610	PAC motif	418	460	8.1E-7
CDD	cd01949	GGDEF	IPR000160	GGDEF domain	472	627	8.56517E-55
Gene3D	G3DSA:3.30.70.270	-	IPR043128	Reverse transcriptase/Diguanylate cyclase domain	471	641	1.9E-51
Gene3D	G3DSA:3.30.450.20	PAS domain	-	-	345	470	2.4E-28
NCBIfam	TIGR00254	JCVI: diguanylate cyclase (GGDEF) domain	IPR000160	GGDEF domain	467	628	7.5E-35
Pfam	PF01590	GAF domain	IPR003018	GAF domain	193	332	5.4E-13
SMART	SM00052	duf2_2	IPR001633	EAL domain	639	885	2.7E-123
SUPERFAMILY	SSF55073	Nucleotide cyclase	IPR029787	Nucleotide cyclase	476	630	1.1E-43
SUPERFAMILY	SSF141868	EAL domain-like	IPR035919	EAL domain superfamily	644	892	8.11E-92
Pfam	PF00563	EAL domain	IPR001633	EAL domain	646	880	6.6E-78
Pfam	PF13426	PAS domain	IPR000014	PAS domain	358	459	1.4E-14
SMART	SM00091	pas_2	IPR000014	PAS domain	346	412	3.8E-6
SUPERFAMILY	SSF55785	PYP-like sensor domain (PAS domain)	IPR035965	PAS domain superfamily	352	458	3.22E-22

Search for additional functional domains at the NCBI CDD database website. Go to this protein's amino acid sequence and follow the link.