Pseudomonas aeruginosa PAO1, PA5091 (hutG)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse PseudoCyc / Metabolic Pathways

Gene Feature Overview

Strain Pseudomonas aeruginosa PAO1 (Stover et al., 2000)
GCF_000006765.1|latest
Locus Tag
PA5091
Name
hutG
Replicon chromosome
Genomic location 5732116 - 5732916 (- strand)
Transposon Mutants 2 transposon mutants in PAO1
Transposon Mutants in orthologs 1 transposon mutants in orthologs

Cross-References

RefSeq NP_253778.1
GI 15600284
Affymetrix PA5091_hutG_at
DNASU PaCD00008189
Entrez 882229
GenBank AAG08476.1
INSDC AAG08476.1
NCBI Locus Tag PA5091
protein_id(GenBank) gb|AAG08476.1|AE004922_1|gnl|PseudoCAP|PA5091
TIGR NTL03PA05092
UniParc UPI00000C5EF8
UniProtKB Acc Q9HU92
UniProtKB ID Q9HU92_PSEAE
UniRef100 UniRef100_W0YZK5
UniRef50 UniRef50_G8Q1M2
UniRef90 UniRef90_A6VDK9

Product

Feature Type CDS
Coding Frame 1
Product Name
N-formylglutamate amidohydrolase
Product Name Confidence: Class 2
Synonyms
Evidence for Translation
Identified using nanoflow high-pressure liquid chromatography (HPLC) in conjunction with microelectrospray ionization on LTQ XL mass spectrometer (PMID:24291602).
Charge (pH 7) -7.21
Kyte-Doolittle Hydrophobicity Value -0.312
Molecular Weight (kDa) 29.8
Isoelectric Point (pI) 5.91

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 121 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG004688 (486 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA5091
Search term: hutG

Human Homologs

References

Purification and properties of formylglutamate amidohydrolase from Pseudomonas putida.
Hu L, Mulfinger LM, Phillips AT
J Bacteriol 1987 Oct;169(10):4696-702
PubMed ID: 3308850
Organization and multiple regulation of histidine utilization genes in Pseudomonas putida.
Hu L, Phillips AT
J Bacteriol 1988 Sep;170(9):4272-9
PubMed ID: 2842309