Pseudomonas aeruginosa PAO1, PA5322 (algC)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse PseudoCyc / Metabolic Pathways

Gene Ontology

Ontology Accession Term GO Evidence Evidence Ontology (ECO) Code Reference Comments
Biological Process GO:0009405 pathogenesis
IMP
Inferred from Mutant Phenotype
ECO:0000015
mutant phenotype evidence
7558335 Reviewed by curator
Biological Process GO:0042121 alginic acid biosynthetic process
IMP
Inferred from Mutant Phenotype
ECO:0000315
mutant phenotype evidence used in manual assertion
22513190 Reviewed by curator
Biological Process GO:0006520 cellular amino acid metabolic process
IDA
Inferred from Direct Assay
ECO:0000002
direct assay evidence
Molecular Function GO:0004615 phosphomannomutase activity
IMP
Inferred from Mutant Phenotype
ECO:0000315
mutant phenotype evidence used in manual assertion
22513190 Reviewed by curator
Biological Process GO:0042121 alginic acid biosynthetic process
IMP
Inferred from Mutant Phenotype
ECO:0000015
mutant phenotype evidence
1903398 Reviewed by curator
Biological Process GO:0009244 lipopolysaccharide core region biosynthetic process
IMP
Inferred from Mutant Phenotype
ECO:0000015
mutant phenotype evidence
7515870 Reviewed by curator
Molecular Function GO:0004614 phosphoglucomutase activity
IMP
Inferred from Mutant Phenotype
ECO:0000015
mutant phenotype evidence
7515870 Reviewed by curator
Molecular Function GO:0004615 phosphomannomutase activity
IMP
Inferred from Mutant Phenotype
ECO:0000015
mutant phenotype evidence
1903398 Reviewed by curator
Biological Process GO:0009243 O antigen biosynthetic process
IMP
Inferred from Mutant Phenotype
ECO:0000315
mutant phenotype evidence used in manual assertion
22513190 Reviewed by curator
Cellular Component GO:0009276 Gram-negative-bacterium-type cell wall
IDA
Inferred from Direct Assay
ECO:0000002
direct assay evidence
Biological Process GO:0005975 carbohydrate metabolic process
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PF02879
ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0016868 intramolecular transferase activity, phosphotransferases
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PR00509
ECO:0000259
match to InterPro signature evidence used in automatic assertion
Biological Process GO:0071704 organic substance metabolic process
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PF00408
ECO:0000259
match to InterPro signature evidence used in automatic assertion

Functional Classifications Manually Assigned by PseudoCAP

Cell wall / LPS / capsule Other PAO1 genes in this class
Amino acid biosynthesis and metabolism Other PAO1 genes in this class
Secreted Factors (toxins, enzymes, alginate) Other PAO1 genes in this class

Pathways

Database Xref Pathway Version Evidence PMID
PseudoCAP Lipopolysaccharide biosynthesis ECO:0000037
not_recorded
PseudoCAP Alginate biosynthesis ECO:0000037
not_recorded
KEGG pae00051 Fructose and mannose metabolism 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion
KEGG pae01120 Microbial metabolism in diverse environments 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion
KEGG pae01100 Metabolic pathways 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion
PseudoCyc PWY-5659 GDP-mannose biosynthesis 19.5 ECO:0000250
sequence similarity evidence used in manual assertion
12867747
KEGG pae00052 Galactose metabolism 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion
KEGG pae00500 Starch and sucrose metabolism 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion
KEGG pae01110 Biosynthesis of secondary metabolites 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion
KEGG pae00521 Streptomycin biosynthesis 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion
PseudoCyc MANGDPMET-PWY GDP-mannose metabolism 19.5 ECO:0000250
sequence similarity evidence used in manual assertion
12867747
PseudoCAP Fructose and mannose metabolism ECO:0000037
not_recorded
KEGG pae00030 Pentose phosphate pathway 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion
PseudoCyc COLANSYN-PWY colanic acid building blocks biosynthesis 19.5 ECO:0000250
sequence similarity evidence used in manual assertion
12867747
KEGG pae00520 Amino sugar and nucleotide sugar metabolism 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion
KEGG pae00230 Purine metabolism 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion
KEGG pae00010 Glycolysis / Gluconeogenesis 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion
KEGG pae01130 Biosynthesis of antibiotics 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion

Functional Predictions from Interpro

Analysis Accession Description Interpro Accession Interpro Description Amino Acid Start Amino Acid Stop E-value
Pfam PF02878 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I IPR005844 Alpha-D-phosphohexomutase, alpha/beta/alpha domain I 418 547 1.3E-36
Gene3D G3DSA:3.40.120.10 - - - 579 656 6.3E-33
Pfam PF02880 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III IPR005846 Alpha-D-phosphohexomutase, alpha/beta/alpha domain III 665 769 1.0E-20
PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature IPR005841 Alpha-D-phosphohexomutase superfamily 506 520 1.0E-24
PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature IPR005841 Alpha-D-phosphohexomutase superfamily 640 655 1.0E-24
PANTHER PTHR43771 PHOSPHOMANNOMUTASE - - 406 858 0.0
SUPERFAMILY SSF53738 Phosphoglucomutase, first 3 domains IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III 561 662 9.81E-33
FunFam G3DSA:3.30.310.50:FF:000007 Phosphomannomutase/phosphoglucomutase - - 776 868 4.1E-51
PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature IPR005841 Alpha-D-phosphohexomutase superfamily 611 624 1.0E-24
MobiDBLite mobidb-lite consensus disorder prediction - - 6 32 -
Gene3D G3DSA:3.40.120.10 - - - 657 775 2.9E-42
SUPERFAMILY SSF53738 Phosphoglucomutase, first 3 domains IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III 665 768 6.67E-33
Gene3D G3DSA:3.30.310.50 - - - 776 868 3.1E-30
FunFam G3DSA:3.40.120.10:FF:000021 Phosphomannomutase/phosphoglucomutase - - 579 656 4.4E-46
SUPERFAMILY SSF53738 Phosphoglucomutase, first 3 domains IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III 417 557 5.49E-39
FunFam G3DSA:3.40.120.10:FF:000001 Phosphoglucosamine mutase - - 415 560 6.8E-45
Pfam PF02879 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II IPR005845 Alpha-D-phosphohexomutase, alpha/beta/alpha domain II 564 660 6.1E-28
MobiDBLite mobidb-lite consensus disorder prediction - - 1 32 -
FunFam G3DSA:3.40.120.10:FF:000025 Phosphomannomutase - - 657 775 1.6E-73
Gene3D G3DSA:3.40.120.10 - - - 406 559 2.9E-49
PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature IPR005841 Alpha-D-phosphohexomutase superfamily 577 596 1.0E-24
CDD cd03089 PMM_PGM - - 418 857 0.0
SUPERFAMILY SSF55957 Phosphoglucomutase, C-terminal domain IPR036900 Alpha-D-phosphohexomutase, C-terminal domain superfamily 775 866 9.24E-26
Pfam PF00408 Phosphoglucomutase/phosphomannomutase, C-terminal domain IPR005843 Alpha-D-phosphohexomutase, C-terminal 780 857 6.7E-14

Search for additional functional domains at the NCBI CDD database website. Go to this protein's amino acid sequence and follow the link.