Pseudomonas fluorescens F113, PSF113_1037 (guaA)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown

Gene Ontology

Ontology Accession Term GO Evidence Evidence Ontology (ECO) Code Reference Comments
Molecular Function GO:0003922 GMP synthase (glutamine-hydrolyzing) activity
ISM
Inferred from Sequence Model
Term mapped from: InterPro:MF_00344
ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0005524 ATP binding
ISM
Inferred from Sequence Model
Term mapped from: InterPro:TIGR00884
ECO:0000259
match to InterPro signature evidence used in automatic assertion
Biological Process GO:0006177 GMP biosynthetic process
ISM
Inferred from Sequence Model
Term mapped from: InterPro:MF_00344
ECO:0000259
match to InterPro signature evidence used in automatic assertion
Biological Process GO:0006164 purine nucleotide biosynthetic process
ISM
Inferred from Sequence Model
Term mapped from: InterPro:TIGR00884
ECO:0000259
match to InterPro signature evidence used in automatic assertion

Functional Classifications Manually Assigned by PseudoCAP

Pathways

Database Xref Pathway Version Evidence PMID
KEGG pfe00230 Purine metabolism 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion
MetaCyc guanosine ribonucleotides <i>de novo</i> biosynthesis InterPro 5.36-75.0 ECO:0000259
match to InterPro signature evidence used in automatic assertion
KEGG pfe01100 Metabolic pathways 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion

Functional Predictions from Interpro

Analysis Accession Description Interpro Accession Interpro Description Amino Acid Start Amino Acid Stop E-value
SUPERFAMILY SSF52402 Adenine nucleotide alpha hydrolases-like - - 197 420 5.51E-57
PANTHER PTHR11922 GMP SYNTHASE-RELATED - - 10 525 0.0
Pfam PF02540 NAD synthase IPR022310 NAD/GMP synthase 215 292 4.5E-8
PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature - - 51 65 4.6E-5
Gene3D G3DSA:3.30.300.10 - - - 411 525 1.1E-48
Pfam PF00117 Glutamine amidotransferase class-I IPR017926 Glutamine amidotransferase 12 200 5.9E-36
SUPERFAMILY SSF52317 Class I glutamine amidotransferase-like IPR029062 Class I glutamine amidotransferase-like 5 204 6.42E-56
NCBIfam TIGR00888 JCVI: glutamine-hydrolyzing GMP synthase, N-terminal domain IPR004739 GMP synthase, glutamine amidotransferase 10 205 1.8E-78
SUPERFAMILY SSF54810 GMP synthetase C-terminal dimerisation domain - - 405 525 2.88E-49
CDD cd01997 GMP_synthase_C IPR001674 GMP synthase, C-terminal 230 524 0.0
Pfam PF00958 GMP synthase C terminal domain IPR001674 GMP synthase, C-terminal 433 524 6.5E-41
FunFam G3DSA:3.40.50.620:FF:000001 GMP synthase [glutamine-hydrolyzing] - - 209 410 4.3E-100
PRINTS PR00096 Glutamine amidotransferase superfamily signature - - 54 63 5.1E-7
NCBIfam TIGR00884 JCVI: glutamine-hydrolyzing GMP synthase, C-terminal domain IPR001674 GMP synthase, C-terminal 213 525 0.0
Gene3D G3DSA:3.40.50.620 HUPs IPR014729 Rossmann-like alpha/beta/alpha sandwich fold 209 410 1.4E-77
PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature - - 81 97 4.6E-5
PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature - - 10 24 4.6E-5
Gene3D G3DSA:3.40.50.880 - IPR029062 Class I glutamine amidotransferase-like 9 206 1.0E-52
FunFam G3DSA:3.40.50.880:FF:000001 GMP synthase [glutamine-hydrolyzing] - - 7 206 4.4E-88
FunFam G3DSA:3.30.300.10:FF:000002 GMP synthase [glutamine-hydrolyzing] - - 411 525 2.5E-54
PRINTS PR00096 Glutamine amidotransferase superfamily signature - - 81 92 5.1E-7
PRINTS PR00096 Glutamine amidotransferase superfamily signature - - 177 190 5.1E-7
Hamap MF_00344 GMP synthase [glutamine-hydrolyzing] [guaA]. IPR022955 GMP synthase 7 525 55.70116
CDD cd01742 GATase1_GMP_Synthase IPR004739 GMP synthase, glutamine amidotransferase 10 198 9.14355E-101

Search for additional functional domains at the NCBI CDD database website. Go to this protein's amino acid sequence and follow the link.