Pseudomonas fluorescens SBW25, PFLU0460 (aceE)
Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
Gene Ontology
| Ontology | Accession | Term | GO Evidence | Evidence Ontology (ECO) Code | Reference | Comments |
|---|---|---|---|---|---|---|
| Molecular Function | GO:0016491 | oxidoreductase activity |
Inferred from Sequence Model
Term mapped from: InterPro:PIRSF000156
|
ECO:0000259 match to InterPro signature evidence used in automatic assertion |
||
| Molecular Function | GO:0003824 | catalytic activity |
Inferred from Sequence Model
Term mapped from: InterPro:G3DSA:3.40.50.920
|
ECO:0000259 match to InterPro signature evidence used in automatic assertion |
Functional Classifications Manually Assigned by PseudoCAP
|
|
Pathways
| Database | Xref | Pathway | Version | Evidence | PMID |
|---|---|---|---|---|---|
| KEGG (InterPro) | 00620 | Pyruvate metabolism | InterPro 5.8-49.0 |
ECO:0000259
match to InterPro signature evidence used in automatic assertion |
0 |
| KEGG (InterPro) | 00900 | Terpenoid backbone biosynthesis | InterPro 5.8-49.0 |
ECO:0000259
match to InterPro signature evidence used in automatic assertion |
0 |
| KEGG (InterPro) | 00730 | Thiamine metabolism | InterPro 5.8-49.0 |
ECO:0000259
match to InterPro signature evidence used in automatic assertion |
0 |
| KEGG (InterPro) | 00010 | Glycolysis / Gluconeogenesis | InterPro 5.8-49.0 |
ECO:0000259
match to InterPro signature evidence used in automatic assertion |
0 |
| KEGG (InterPro) | 00020 | Citrate cycle (TCA cycle) | InterPro 5.8-49.0 |
ECO:0000259
match to InterPro signature evidence used in automatic assertion |
0 |
| UniPathway | UPA00064 | 1-deoxy-D-xylulose 5-phosphate biosynthesis | InterPro 5.8-49.0 |
ECO:0000259
match to InterPro signature evidence used in automatic assertion |
0 |
Functional Predictions from Interpro
| Analysis | Accession | Description | Interpro Accession | Interpro Description | Amino Acid Start | Amino Acid Stop | E-value |
|---|---|---|---|---|---|---|---|
| PIRSF | PIRSF000156 | Pyruvate_dh_E1 | IPR004660 | Pyruvate dehydrogenase E1 component | 1 | 881 | 0.0 |
| Gene3D | G3DSA:3.40.50.920 | - | IPR009014 | Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II | 698 | 880 | 4.8E-80 |
| SUPERFAMILY | SSF52922 | TK C-terminal domain-like | IPR009014 | Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II | 693 | 879 | 1.92E-60 |
| Gene3D | G3DSA:3.40.50.970 | - | - | - | 51 | 463 | 0.0 |
| Pfam | PF17831 | Pyruvate dehydrogenase E1 component middle domain | IPR041621 | Pyruvate dehydrogenase E1 component, middle domain | 472 | 691 | 2.4E-118 |
| NCBIfam | TIGR00759 | JCVI: pyruvate dehydrogenase (acetyl-transferring), homodimeric type | IPR004660 | Pyruvate dehydrogenase E1 component | 2 | 879 | 0.0 |
| FunFam | G3DSA:3.40.50.970:FF:000011 | Pyruvate dehydrogenase E1 component | - | - | 51 | 463 | 0.0 |
| SUPERFAMILY | SSF52518 | Thiamin diphosphate-binding fold (THDP-binding) | IPR029061 | Thiamin diphosphate-binding fold | 466 | 692 | 4.47E-96 |
| SUPERFAMILY | SSF52518 | Thiamin diphosphate-binding fold (THDP-binding) | IPR029061 | Thiamin diphosphate-binding fold | 52 | 459 | 0.0 |
| Pfam | PF00456 | Transketolase, thiamine diphosphate binding domain | IPR005474 | Transketolase, N-terminal | 196 | 287 | 2.3E-6 |
| CDD | cd02017 | TPP_E1_EcPDC_like | IPR035807 | Pyruvate dehydrogenase E1 component, N-terminal | 70 | 453 | 0.0 |
| Gene3D | G3DSA:3.40.50.970 | - | - | - | 464 | 697 | 5.2E-113 |
| PANTHER | PTHR43825 | PYRUVATE DEHYDROGENASE E1 COMPONENT | - | - | 62 | 855 | 0.0 |
Search for additional functional domains at the NCBI CDD database website. Go to this protein's amino acid sequence and follow the link.