Pseudomonas aeruginosa UCBPP-PA14, PA14_61210 (hprA)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse View in GBrowse

Gene Ontology

Ontology Accession Term GO Evidence Evidence Ontology (ECO) Code Reference Comments
Molecular Function GO:0051287 NAD binding
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PF02826
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0016616 oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PF00389
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Biological Process GO:0055114 oxidation-reduction process
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PF02826
 ECO:0000259
match to InterPro signature evidence used in automatic assertion

Functional Classifications Manually Assigned by PseudoCAP

Central intermediary metabolism Other UCBPP-PA14 genes in this class

Pathways

Database Xref Pathway Version Evidence PMID
KEGG pau01120 Microbial metabolism in diverse environments 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion
KEGG pau01100 Metabolic pathways 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion
KEGG pau00680 Methane metabolism 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion
KEGG pau01110 Biosynthesis of secondary metabolites 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion
KEGG pau01200 Carbon metabolism 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion
KEGG pau01130 Biosynthesis of antibiotics 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion
KEGG pau00260 Glycine, serine and threonine metabolism 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion
KEGG pau00630 Glyoxylate and dicarboxylate metabolism 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion

Functional Predictions from Interpro

Analysis Accession Description Interpro Accession Interpro Description Amino Acid Start Amino Acid Stop E-value
CDD cd12162 2-Hacid_dh_4 5 311 6.13502E-149
Pfam PF02826 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain IPR006140 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain 112 290 5.2E-52
Gene3D G3DSA:3.40.50.720 20 317 7.8E-111
Pfam PF00389 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain IPR006139 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain 20 320 8.1E-26
SUPERFAMILY SSF52283 17 141 3.97E-29
SUPERFAMILY SSF51735 IPR036291 NAD(P)-binding domain superfamily 106 291 3.2E-52
Gene3D G3DSA:3.40.50.720 102 289 7.8E-111
ProSitePatterns PS00671 D-isomer specific 2-hydroxyacid dehydrogenases signature 3. IPR029753 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site 227 243 -

Search for additional functional domains at the NCBI CDD database website. Go to this protein's amino acid sequence and follow the link.