Pseudomonas aeruginosa UCBPP-PA14, PA14_71870 (uvrD)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
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Gene Ontology

Ontology Accession Term GO Evidence Evidence Ontology (ECO) Code Reference Comments
Biological Process GO:0006298 mismatch repair
ISS
Inferred from Sequence or Structural Similarity
Term mapped from: PseudoCAP:PA5443
 ECO:0000249
sequence similarity evidence used in automatic assertion		 11952911
Molecular Function GO:0003677 DNA binding
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PTHR11070
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0003678 DNA helicase activity
ISM
Inferred from Sequence Model
Term mapped from: InterPro:TIGR01075
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0005524 ATP binding
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PF00580
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Biological Process GO:0006268 DNA unwinding involved in DNA replication
ISM
Inferred from Sequence Model
Term mapped from: InterPro:TIGR01075
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Cellular Component GO:0005737 cytoplasm
ISM
Inferred from Sequence Model
Term mapped from: InterPro:TIGR01075
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0016787 hydrolase activity
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PF13361
 ECO:0000259
match to InterPro signature evidence used in automatic assertion

Functional Classifications Manually Assigned by PseudoCAP

DNA replication, recombination, modification and repair Other UCBPP-PA14 genes in this class

Pathways

Database Xref Pathway Version Evidence PMID
KEGG pau03420 Nucleotide excision repair 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion
KEGG pau03430 Mismatch repair 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion

Functional Predictions from Interpro

Analysis Accession Description Interpro Accession Interpro Description Amino Acid Start Amino Acid Stop E-value
Gene3D G3DSA:3.40.50.300 - IPR027417 P-loop containing nucleoside triphosphate hydrolase 283 638 0.0
Coils Coil Coil - - 725 728 -
Gene3D G3DSA:3.40.50.300 - IPR027417 P-loop containing nucleoside triphosphate hydrolase 12 275 1.1E-102
Gene3D G3DSA:1.10.486.10 PCRA; domain 4 - - 384 540 0.0
PANTHER PTHR11070 UVRD / RECB / PCRA DNA HELICASE FAMILY MEMBER IPR000212 DNA helicase, UvrD/REP type 10 647 0.0
Gene3D G3DSA:1.10.10.160 - IPR013986 DExx box DNA helicase domain superfamily 116 189 1.1E-102
CDD cd17932 DEXQc_UvrD - - 16 285 5.45995E-89
Pfam PF00580 UvrD/REP helicase N-terminal domain IPR014016 UvrD-like helicase, ATP-binding domain 12 273 6.8E-74
Pfam PF13361 UvrD-like helicase C-terminal domain IPR014017 UvrD-like DNA helicase, C-terminal 279 618 3.1E-78
FunFam G3DSA:3.40.50.300:FF:001201 ATP-dependent DNA helicase UvrD2 - - 282 385 8.3E-34
CDD cd18807 SF1_C_UvrD - - 287 616 3.38023E-30
FunFam G3DSA:1.10.486.10:FF:000001 DNA helicase - - 384 540 1.1E-73
NCBIfam TIGR01075 JCVI: DNA helicase UvrD IPR005753 DNA helicase, ATP-dependent, UvrD type 8 726 0.0
FunFam G3DSA:1.10.10.160:FF:000002 DNA helicase - - 116 189 2.2E-28
SUPERFAMILY SSF52540 P-loop containing nucleoside triphosphate hydrolases IPR027417 P-loop containing nucleoside triphosphate hydrolase 9 644 0.0

Search for additional functional domains at the NCBI CDD database website. Go to this protein's amino acid sequence and follow the link.