Pseudomonas aeruginosa M18, PAM18_0037 (trpB)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown

Gene Ontology

Ontology Accession Term GO Evidence Evidence Ontology (ECO) Code Reference Comments
Molecular Function GO:0004834 tryptophan synthase activity
ISM
Inferred from Sequence Model
Term mapped from: InterPro:TIGR00263
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Biological Process GO:0000162 tryptophan biosynthetic process
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PIRSF001413
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Biological Process GO:0006568 tryptophan metabolic process
ISM
Inferred from Sequence Model
Term mapped from: InterPro:TIGR00263
 ECO:0000259
match to InterPro signature evidence used in automatic assertion

Functional Classifications Manually Assigned by PseudoCAP

Amino acid biosynthesis and metabolism Other M18 genes in this class

Pathways

Database Xref Pathway Version Evidence PMID
KEGG paf01130 Biosynthesis of antibiotics 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion
KEGG paf00260 Glycine, serine and threonine metabolism 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion
KEGG paf01100 Metabolic pathways 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion
KEGG paf01230 Biosynthesis of amino acids 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion
KEGG paf00400 Phenylalanine, tyrosine and tryptophan biosynthesis 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion
KEGG paf01110 Biosynthesis of secondary metabolites 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion

Functional Predictions from Interpro

Analysis Accession Description Interpro Accession Interpro Description Amino Acid Start Amino Acid Stop E-value
Hamap MF_00133 Tryptophan synthase beta chain [trpB]. IPR023026 Tryptophan synthase beta chain/beta chain-like 7 396 52.810528
CDD cd06446 Trp-synth_B IPR006654 Tryptophan synthase, beta chain 32 392 0.0
SUPERFAMILY SSF53686 Tryptophan synthase beta subunit-like PLP-dependent enzymes IPR036052 Tryptophan synthase beta chain-like, PALP domain superfamily 8 394 0.0
PIRSF PIRSF001413 Trp_syn_beta IPR023026 Tryptophan synthase beta chain/beta chain-like 4 402 0.0
Pfam PF00291 Pyridoxal-phosphate dependent enzyme IPR001926 Tryptophan synthase beta chain-like, PALP domain 58 383 3.6E-46
FunFam G3DSA:3.40.50.1100:FF:000001 Tryptophan synthase beta chain - - 78 210 1.4E-63
FunFam G3DSA:3.40.50.1100:FF:000004 Tryptophan synthase beta chain - - 211 389 4.1E-85
PANTHER PTHR48077 TRYPTOPHAN SYNTHASE-RELATED IPR023026 Tryptophan synthase beta chain/beta chain-like 14 399 0.0
NCBIfam TIGR00263 JCVI: tryptophan synthase subunit beta IPR006654 Tryptophan synthase, beta chain 12 395 0.0
Gene3D G3DSA:3.40.50.1100 - IPR036052 Tryptophan synthase beta chain-like, PALP domain superfamily 59 390 0.0
Gene3D G3DSA:3.40.50.1100 - IPR036052 Tryptophan synthase beta chain-like, PALP domain superfamily 14 211 0.0

Search for additional functional domains at the NCBI CDD database website. Go to this protein's amino acid sequence and follow the link.