Pseudomonas aeruginosa M18, PAM18_0093 (vgrG1)
Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
Gene Feature Overview
| Strain |
Pseudomonas aeruginosa M18
GCF_000226155.1|latest |
| Locus Tag |
PAM18_0093
|
| Name |
vgrG1
|
| Replicon | chromosome |
| Genomic location | 109416 - 111356 (+ strand) |
Cross-References
| RefSeq | YP_005972684.1 |
| GI | 386056162 |
| Entrez | 12564110 |
| NCBI Locus Tag | PAM18_0093 |
Product
| Feature Type | CDS |
| Coding Frame | 1 |
| Product Name |
VgrG1
|
| Synonyms | |
| Evidence for Translation | |
| Charge (pH 7) | -7.09 |
| Kyte-Doolittle Hydrophobicity Value | -0.531 |
| Molecular Weight (kDa) | 72.3 |
| Isoelectric Point (pI) | 6.28 |
Subcellular localization
| Individual Mappings | |
| Additional evidence for subcellular localization |
AlphaFold 2 Protein Structure Predictions
Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.
PDB 3D Structures
| Accession | Header | Accession Date | Compound | Source | Resolution | Method | Percent Identity |
| 4UHV | STRUCTURAL PROTEIN | 03/25/15 | The structure of VgrG1, the needle tip of the bacterial Type VI Secretion System | PSEUDOMONAS AERUGINOSA | 2 | X-RAY DIFFRACTION | 99.8 |
| 6H3L | TOXIN | 07/19/18 | Structure of VgrG1 in the Type VI secretion pre-firing VgrG1-Tse6-EagT6-EF-Tu-Tsi6 complex | Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1) | 4.2 | ELECTRON MICROSCOPY | 99.8 |
| 6H3N | TOXIN | 07/19/18 | Structure of VgrG1 in the Type VI secretion VgrG1-Tse6-EF-Tu complex embedded in lipid nanodiscs | Pseudomonas aeruginosa PAO1 | 3.25 | ELECTRON MICROSCOPY | 99.8 |
| 4MTK | TOXIN | 09/19/13 | Crystal structure of PA0091 VgrG1, the central spike of the Type VI Secretion System | Pseudomonas aeruginosa | 3.322 | X-RAY DIFFRACTION | 99.8 |
Pathogen Association Analysis
| Results |
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 156 genera
|
Orthologs/Comparative Genomics
| Pseudomonas Ortholog Database | View orthologs at Pseudomonas Ortholog Database |
| Pseudomonas Ortholog Group |
POG000090 (3342 members) |
| Putative Inparalogs | None Found |
Interactions
| STRING database | Search for predicted protein-protein interactions using:
Search term: PAM18_0093
Search term: vgrG1
Search term: VgrG1
|
Human Homologs
References
No references are associated with this feature.