Pseudomonas aeruginosa M18, PAM18_5565 (uvrD)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in GBrowse

Gene Ontology

Ontology Accession Term GO Evidence Evidence Ontology (ECO) Code Reference Comments
Biological Process GO:0006298 mismatch repair
ISS
Inferred from Sequence or Structural Similarity
Term mapped from: PseudoCAP:PA5443
ECO:0000249
sequence similarity evidence used in automatic assertion
11952911
Biological Process GO:0006268 DNA unwinding involved in DNA replication
ISM
Inferred from Sequence Model
Term mapped from: InterPro:TIGR01075
ECO:0000259
match to InterPro signature evidence used in automatic assertion
Cellular Component GO:0005737 cytoplasm
ISM
Inferred from Sequence Model
Term mapped from: InterPro:TIGR01075
ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0005524 ATP binding
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PF13361
ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0003678 DNA helicase activity
ISM
Inferred from Sequence Model
Term mapped from: InterPro:TIGR01075
ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0016787 hydrolase activity
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PF13361
ECO:0000259
match to InterPro signature evidence used in automatic assertion

Functional Classifications Manually Assigned by PseudoCAP

DNA replication, recombination, modification and repair Other M18 genes in this class

Pathways

Database Xref Pathway Version Evidence PMID
KEGG paf03430 Mismatch repair 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion
KEGG paf03420 Nucleotide excision repair 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion

Functional Predictions from Interpro

Analysis Accession Description Interpro Accession Interpro Description Amino Acid Start Amino Acid Stop E-value
ProSiteProfiles PS51217 UvrD-like DNA helicase C-terminal domain profile. IPR014017 UvrD-like DNA helicase, C-terminal 289 566 25.557
SUPERFAMILY SSF52540 IPR027417 P-loop containing nucleoside triphosphate hydrolase 9 644 0.0
CDD cd17932 DEXQc_UvrD 16 285 4.22801E-89
Pfam PF00580 UvrD/REP helicase N-terminal domain IPR034739 UvrD/AddA helicase, N-terminal 12 273 6.4E-74
Gene3D G3DSA:1.10.10.160 IPR013986 DExx box DNA helicase domain superfamily 116 189 3.6E-99
Gene3D G3DSA:1.10.486.10 384 540 1.5E-130
Pfam PF13361 UvrD-like helicase C-terminal domain IPR014017 UvrD-like DNA helicase, C-terminal 279 618 1.4E-75
ProSiteProfiles PS51198 UvrD-like DNA helicase ATP-binding domain profile. IPR014016 UvrD-like helicase, ATP-binding domain 10 288 54.852
TIGRFAM TIGR01075 uvrD: DNA helicase II IPR005753 DNA helicase, ATP-dependent, UvrD type 8 726 0.0
Gene3D G3DSA:3.40.50.300 12 275 3.6E-99
CDD cd18807 SF1_C_UvrD 287 616 5.00011E-31
Gene3D G3DSA:3.40.50.300 283 638 1.5E-130

Search for additional functional domains at the NCBI CDD database website. Go to this protein's amino acid sequence and follow the link.