Pseudomonas aeruginosa DK2, PADK2_02220

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown

Gene Ontology

Ontology Accession Term GO Evidence Evidence Ontology (ECO) Code Reference Comments
Molecular Function GO:0051536 iron-sulfur cluster binding
ISM
Inferred from Sequence Model
Term mapped from: InterPro:G3DSA:1.10.1060.10
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0016491 oxidoreductase activity
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PF07992
 ECO:0000259
match to InterPro signature evidence used in automatic assertion

Functional Classifications Manually Assigned by PseudoCAP

Putative enzymes Other DK2 genes in this class

Pathways

Database Xref Pathway Version Evidence PMID
KEGG pdk00770 Pantothenate and CoA biosynthesis 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion
KEGG pdk00240 Pyrimidine metabolism 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion
KEGG pdk00410 beta-Alanine metabolism 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion
KEGG pdk01100 Metabolic pathways 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion

Functional Predictions from Interpro

Analysis Accession Description Interpro Accession Interpro Description Amino Acid Start Amino Acid Stop E-value
PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature - - 276 294 2.7E-19
PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature - - 142 164 1.2E-9
Pfam PF14691 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster IPR028261 Dihydroprymidine dehydrogenase domain II 20 126 5.2E-33
SUPERFAMILY SSF51971 Nucleotide-binding domain - - 139 381 7.65E-51
PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature - - 372 388 2.7E-19
PANTHER PTHR43073 DIHYDROPYRIMIDINE DEHYDROGENASE [NADP(+)] - - 18 449 2.8E-71
SUPERFAMILY SSF46548 alpha-helical ferredoxin - - 15 151 1.52E-27
Gene3D G3DSA:3.50.50.60 - IPR036188 FAD/NAD(P)-binding domain superfamily 273 455 2.5E-23
PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature - - 401 423 2.7E-19
PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature - - 411 429 1.2E-9
Gene3D G3DSA:1.10.1060.10 - IPR009051 Alpha-helical ferredoxin 9 138 1.7E-33
Gene3D G3DSA:3.50.50.60 - IPR036188 FAD/NAD(P)-binding domain superfamily 139 258 3.9E-27
Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase IPR023753 FAD/NAD(P)-binding domain 141 437 1.5E-30
PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature - - 143 162 2.7E-19
PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature - - 272 296 1.2E-9

Search for additional functional domains at the NCBI CDD database website. Go to this protein's amino acid sequence and follow the link.