Pseudomonas aeruginosa DK2, PADK2_02535 (bioD)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown

Gene Ontology

Ontology Accession Term GO Evidence Evidence Ontology (ECO) Code Reference Comments
Molecular Function GO:0005524 ATP binding
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PIRSF006755
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0000287 magnesium ion binding
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PIRSF006755
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0004141 dethiobiotin synthase activity
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PIRSF006755
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Biological Process GO:0009102 biotin biosynthetic process
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PIRSF006755
 ECO:0000259
match to InterPro signature evidence used in automatic assertion

Functional Classifications Manually Assigned by PseudoCAP

Biosynthesis of cofactors, prosthetic groups and carriers Other DK2 genes in this class

Pathways

Database Xref Pathway Version Evidence PMID
KEGG pdk00780 Biotin metabolism 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion
KEGG pdk01100 Metabolic pathways 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion

Functional Predictions from Interpro

Analysis Accession Description Interpro Accession Interpro Description Amino Acid Start Amino Acid Stop E-value
PANTHER PTHR43210 DETHIOBIOTIN SYNTHETASE IPR004472 Dethiobiotin synthase BioD 1 217 1.8E-59
SUPERFAMILY SSF52540 P-loop containing nucleoside triphosphate hydrolases IPR027417 P-loop containing nucleoside triphosphate hydrolase 1 214 6.02E-60
CDD cd03109 DTBS - - 2 194 2.57187E-47
Gene3D G3DSA:3.40.50.300 - IPR027417 P-loop containing nucleoside triphosphate hydrolase 3 222 2.1E-68
Pfam PF13500 AAA domain - - 4 212 1.3E-35
NCBIfam TIGR00347 JCVI: dethiobiotin synthase IPR004472 Dethiobiotin synthase BioD 5 176 6.2E-44
FunFam G3DSA:3.40.50.300:FF:000292 ATP-dependent dethiobiotin synthetase BioD - - 2 224 5.5E-80
Hamap MF_00336 ATP-dependent dethiobiotin synthetase BioD [bioD]. IPR004472 Dethiobiotin synthase BioD 1 218 28.999653
PIRSF PIRSF006755 DTB_synth IPR004472 Dethiobiotin synthase BioD 1 226 1.9E-76

Search for additional functional domains at the NCBI CDD database website. Go to this protein's amino acid sequence and follow the link.