Pseudomonas aeruginosa DK2, PADK2_06480

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown

Gene Ontology

Ontology Accession Term GO Evidence Evidence Ontology (ECO) Code Reference Comments
Biological Process GO:0051051 negative regulation of transport
ISS
Inferred from Sequence or Structural Similarity
Term mapped from: PseudoCAP:PA3574
ECO:0000249
sequence similarity evidence used in automatic assertion
15855496
Molecular Function GO:0003677 DNA binding
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PF00440
ECO:0000259
match to InterPro signature evidence used in automatic assertion

Functional Classifications Manually Assigned by PseudoCAP

Transcriptional regulators Other DK2 genes in this class
Antibiotic resistance and susceptibility Other DK2 genes in this class

Pathways

Database Xref Pathway Version Evidence PMID
KEGG pdk01501 beta-Lactam resistance 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion

Functional Predictions from Interpro

Analysis Accession Description Interpro Accession Interpro Description Amino Acid Start Amino Acid Stop E-value
FunFam G3DSA:1.10.357.10:FF:000003 HTH-type transcriptional regulator AcrR - - 1 212 1.4E-83
SUPERFAMILY SSF46689 Homeodomain-like IPR009057 Homeobox-like domain superfamily 1 65 7.98E-19
Pfam PF08361 MAATS-type transcriptional repressor, C-terminal region IPR013572 Transcription regulator MAATS, C-terminal 83 198 3.0E-13
PRINTS PR00455 TetR bacterial regulatory protein HTH signature IPR001647 DNA-binding HTH domain, TetR-type 15 28 6.8E-12
PANTHER PTHR30055 HTH-TYPE TRANSCRIPTIONAL REGULATOR RUTR - - 2 207 4.4E-26
SUPERFAMILY SSF48498 Tetracyclin repressor-like, C-terminal domain IPR036271 Tetracyclin repressor-like, C-terminal domain superfamily 83 202 7.56E-12
FunFam G3DSA:1.10.10.60:FF:000141 TetR family transcriptional regulator - - 8 59 3.8E-15
Pfam PF00440 Bacterial regulatory proteins, tetR family IPR001647 DNA-binding HTH domain, TetR-type 15 61 7.9E-18
Gene3D G3DSA:1.10.357.10 Tetracycline Repressor, domain 2 - - 1 212 5.6E-98
PRINTS PR00455 TetR bacterial regulatory protein HTH signature IPR001647 DNA-binding HTH domain, TetR-type 36 59 6.8E-12

Search for additional functional domains at the NCBI CDD database website. Go to this protein's amino acid sequence and follow the link.