Pseudomonas aeruginosa DK2, PADK2_28935

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown

Gene Ontology

Ontology Accession Term GO Evidence Evidence Ontology (ECO) Code Reference Comments
Biological Process GO:0006006 glucose metabolic process
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PIRSF000110
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0004345 glucose-6-phosphate dehydrogenase activity
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PF02781
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0050661 NADP binding
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PIRSF000110
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0016614 oxidoreductase activity, acting on CH-OH group of donors
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PIRSF000110
 ECO:0000259
match to InterPro signature evidence used in automatic assertion

Functional Classifications Manually Assigned by PseudoCAP

Energy metabolism Other DK2 genes in this class

Pathways

Database Xref Pathway Version Evidence PMID
KEGG pdk01120 Microbial metabolism in diverse environments 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion
KEGG pdk01200 Carbon metabolism 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion
KEGG pdk01110 Biosynthesis of secondary metabolites 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion
KEGG pdk01100 Metabolic pathways 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion
KEGG pdk00480 Glutathione metabolism 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion
KEGG pdk00030 Pentose phosphate pathway 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion
KEGG pdk01130 Biosynthesis of antibiotics 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion

Functional Predictions from Interpro

Analysis Accession Description Interpro Accession Interpro Description Amino Acid Start Amino Acid Stop E-value
PRINTS PR00079 Glucose-6-phosphate dehydrogenase signature IPR001282 Glucose-6-phosphate dehydrogenase 220 237 6.5E-49
PRINTS PR00079 Glucose-6-phosphate dehydrogenase signature IPR001282 Glucose-6-phosphate dehydrogenase 238 254 6.5E-49
PANTHER PTHR23429 GLUCOSE-6-PHOSPHATE 1-DEHYDROGENASE G6PD IPR001282 Glucose-6-phosphate dehydrogenase 8 485 0.0
Pfam PF00479 Glucose-6-phosphate dehydrogenase, NAD binding domain IPR022674 Glucose-6-phosphate dehydrogenase, NAD-binding 14 188 5.2E-54
SUPERFAMILY SSF55347 Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain - - 178 487 3.6E-116
Hamap MF_00966 Glucose-6-phosphate 1-dehydrogenase [zwf]. IPR001282 Glucose-6-phosphate dehydrogenase 9 488 82.424065
Gene3D G3DSA:3.30.360.10 Dihydrodipicolinate Reductase; domain 2 - - 178 476 0.0
SUPERFAMILY SSF51735 NAD(P)-binding Rossmann-fold domains IPR036291 NAD(P)-binding domain superfamily 5 191 3.74E-53
PRINTS PR00079 Glucose-6-phosphate dehydrogenase signature IPR001282 Glucose-6-phosphate dehydrogenase 329 355 6.5E-49
PRINTS PR00079 Glucose-6-phosphate dehydrogenase signature IPR001282 Glucose-6-phosphate dehydrogenase 168 196 6.5E-49
NCBIfam TIGR00871 JCVI: glucose-6-phosphate dehydrogenase IPR001282 Glucose-6-phosphate dehydrogenase 9 486 0.0
PRINTS PR00079 Glucose-6-phosphate dehydrogenase signature IPR001282 Glucose-6-phosphate dehydrogenase 144 157 6.5E-49
Gene3D G3DSA:3.40.50.720 - - - 12 436 0.0
Pfam PF02781 Glucose-6-phosphate dehydrogenase, C-terminal domain IPR022675 Glucose-6-phosphate dehydrogenase, C-terminal 190 486 3.1E-123
PIRSF PIRSF000110 G6PD IPR001282 Glucose-6-phosphate dehydrogenase 1 488 0.0

Search for additional functional domains at the NCBI CDD database website. Go to this protein's amino acid sequence and follow the link.