Pseudomonas aeruginosa B136-33, G655_02190

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown

Gene Ontology

Ontology Accession Term GO Evidence Evidence Ontology (ECO) Code Reference Comments
Cellular Component GO:0005829 cytosol
ISM
Inferred from Sequence Model
Term mapped from: InterPro:TIGR00676
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0004489 methylenetetrahydrofolate reductase (NAD(P)H) activity
ISM
Inferred from Sequence Model
Term mapped from: InterPro:cd00537
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Biological Process GO:0009086 methionine biosynthetic process
ISM
Inferred from Sequence Model
Term mapped from: InterPro:TIGR00676
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Biological Process GO:0006555 methionine metabolic process
ISM
Inferred from Sequence Model
Term mapped from: InterPro:cd00537
 ECO:0000259
match to InterPro signature evidence used in automatic assertion

Functional Classifications Manually Assigned by PseudoCAP

Central intermediary metabolism Other B136-33 genes in this class
Amino acid biosynthesis and metabolism Other B136-33 genes in this class

Pathways

Database Xref Pathway Version Evidence PMID
KEGG psg01200 Carbon metabolism 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion
KEGG psg00670 One carbon pool by folate 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion
KEGG psg01100 Metabolic pathways 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion
KEGG psg01120 Microbial metabolism in diverse environments 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion

Functional Predictions from Interpro

Analysis Accession Description Interpro Accession Interpro Description Amino Acid Start Amino Acid Stop E-value
Gene3D G3DSA:3.20.20.220 - - - 1 281 4.5E-92
FunFam G3DSA:3.20.20.220:FF:000014 Methylenetetrahydrofolate reductase - - 1 281 0.0
SUPERFAMILY SSF51730 FAD-linked oxidoreductase IPR029041 FAD-linked oxidoreductase-like 3 280 3.14E-95
PANTHER PTHR45754 METHYLENETETRAHYDROFOLATE REDUCTASE - - 2 280 2.3E-81
CDD cd00537 MTHFR IPR003171 Methylenetetrahydrofolate reductase-like 8 278 4.7871E-126
Pfam PF02219 Methylenetetrahydrofolate reductase IPR003171 Methylenetetrahydrofolate reductase-like 4 278 3.7E-88
NCBIfam TIGR00676 JCVI: methylenetetrahydrofolate reductase [NAD(P)H] IPR004620 5,10-methylenetetrahydrofolate reductase 8 279 5.5E-100

Search for additional functional domains at the NCBI CDD database website. Go to this protein's amino acid sequence and follow the link.