Pseudomonas aeruginosa RP73, M062_00275

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown

Gene Ontology

Ontology Accession Term GO Evidence Evidence Ontology (ECO) Code Reference Comments
Biological Process GO:0006529 asparagine biosynthetic process
ISM
Inferred from Sequence Model
Term mapped from: InterPro:cd01991
ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0004066 asparagine synthase (glutamine-hydrolyzing) activity
ISM
Inferred from Sequence Model
Term mapped from: InterPro:cd01991
ECO:0000259
match to InterPro signature evidence used in automatic assertion

Functional Classifications Manually Assigned by PseudoCAP

Putative enzymes Other RP73 genes in this class

Pathways

Database Xref Pathway Version Evidence PMID
KEGG prp00250 Alanine, aspartate and glutamate metabolism 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion
KEGG prp01100 Metabolic pathways 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion
KEGG prp01110 Biosynthesis of secondary metabolites 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion

Functional Predictions from Interpro

Analysis Accession Description Interpro Accession Interpro Description Amino Acid Start Amino Acid Stop E-value
SUPERFAMILY SSF52402 Adenine nucleotide alpha hydrolases-like - - 231 578 7.33E-60
PANTHER PTHR43284 ASPARAGINE SYNTHETASE (GLUTAMINE-HYDROLYZING) - - 1 606 0.0
Gene3D G3DSA:3.40.50.620 HUPs IPR014729 Rossmann-like alpha/beta/alpha sandwich fold 224 592 1.3E-59
Gene3D G3DSA:3.60.20.10 Glutamine Phosphoribosylpyrophosphate, subunit 1, domain 1 IPR029055 Nucleophile aminohydrolases, N-terminal 11 223 1.1E-59
NCBIfam TIGR01536 JCVI: asparagine synthase (glutamine-hydrolyzing) IPR006426 Asparagine synthase, glutamine-hydrolyzing 2 537 0.0
SUPERFAMILY SSF56235 N-terminal nucleophile aminohydrolases (Ntn hydrolases) IPR029055 Nucleophile aminohydrolases, N-terminal 1 226 9.44E-62
PIRSF PIRSF001589 Asn_synthetase_glu-h IPR006426 Asparagine synthase, glutamine-hydrolyzing 1 610 0.0
Pfam PF00733 Asparagine synthase IPR001962 Asparagine synthase 242 604 4.6E-82
Pfam PF13537 Glutamine amidotransferase domain IPR017932 Glutamine amidotransferase type 2 domain 48 170 4.2E-43
CDD cd01991 Asn_Synthase_B_C IPR001962 Asparagine synthase 243 538 3.22018E-62
CDD cd00712 AsnB IPR033738 Asparagine synthase, N-terminal domain 2 225 3.51368E-100

Search for additional functional domains at the NCBI CDD database website. Go to this protein's amino acid sequence and follow the link.